Volume 20, Issue 18
Preparative Organic Chemistry
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ChemInform Abstract: Thiazolium C(2)-Proton Exchange: Isotope Effects, Internal Return, and a Small Intrinsic Barrier.

M. W. WASHABAUGH

M. W. WASHABAUGH

Grad. Dep. Biochem., Brandeis Univ., Waltham, MA 02254, USA

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W. P. JENCKS

W. P. JENCKS

Grad. Dep. Biochem., Brandeis Univ., Waltham, MA 02254, USA

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First published: May 2, 1989

ChemInform Abstract

Evidence is described that the proton-transfer reactions (see foregoing ref.) proceed through a free carbanion intermediate, as expected for a normal acid, and that thiazolium ions are the most normal carbon acids yet identified.

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