Volume 20, Issue 2
Heterocyclic Compounds
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ChemInform Abstract: Studies on Mannich Reaction of 1-Benzyltetrahydroisoquinolines.

D. S. BHAKUNI

D. S. BHAKUNI

Central Drug Res. Inst., Lucknow-226001, India

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P. KUMAR

P. KUMAR

Central Drug Res. Inst., Lucknow-226001, India

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First published: January 10, 1989

Abstract

Mannich cyclization of the tetrahydroisoquinolines (I), (V), or (VII) yields p- and/or o-cyclization products as shown in the reaction scheme.

ChemInform Abstract

Mannich cyclization of the tetrahydroisoquinolines (I), (V), or (VII) yields p- and/or o-cyclization products as shown in the reaction scheme. The N-methyl derivative (X) is obtained from the bromodimethoxybenzyl compound (IX) under the same conditions.

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