Preparative Organic Chemistry
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ChemInform Abstract: Syntheses and Flash Vacuum Pyrolyses of Highly Functionalized α-N-Hydroxy Amino Acids.
First published: January 10, 1989
Abstract
Flash vacuum pyrolysis of the sulfoxide (XII), prepared from L-methionine (I) via the N-hydroxy amino acid ester (VI), gives the vinyldihydropyridone (XIII) instead of a carbacephalosporin.
ChemInform Abstract
Flash vacuum pyrolysis of the sulfoxide (XII), prepared from L-methionine (I) via the N-hydroxy amino acid ester (VI), gives the vinyldihydropyridone (XIII) instead of a carbacephalosporin. Similarly, pyrolysis of the diene (XV) does not form the carbacephalosporin skeleton, but produces a mixture of the dihydropyridones (XVI) and (XVII).
