Preparative Organic Chemistry
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ChemInform Abstract: Fused Sulfolanes. Part 1. Synthesis and Rearrangement of trans-2-Iminoperhydrothieno(3,4-d)oxazol-5,5-dioxides.
First published: August 16, 1988
Abstract
The aminohydroxysulfolane (I) reacts with the isothiocyanates (II) to give the corresponding thioureas which are cyclized in situ, producing the iminooxazoles (III).
ChemInform Abstract
The aminohydroxysulfolane (I) reacts with the isothiocyanates (II) to give the corresponding thioureas which are cyclized in situ, producing the iminooxazoles (III). Basic treatment of (IIIa) - (IIId) yields the rearranged imidazolones (IVa) - (IVd). (IVa) and (IVc) are also prepared from (Va) or (Vc) and cyanogen bromide (VI).
