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ChemInform Abstract: 2,2′-Carbonyl-bis(3,5-dioxo-4-methyl-1,2,4-oxadiazolidine). Part 2. Reagent for the Direct Esterification of Carboxylic Acids.
First published: May 3, 1988
Abstract
The N-protected amino acids (I) react with the carbonylbis(oxadiazolidine) (II) to give the mixed anhydrides (III) which are treated with 4-dimethylaminopyridine (IV) to produce the salts (V).
ChemInform Abstract
The N-protected amino acids (I) react with the carbonylbis(oxadiazolidine) (II) to give the mixed anhydrides (III) which are treated with 4-dimethylaminopyridine (IV) to produce the salts (V). These react with some alcohols such as (VI), yielding the amino esters (VII).
