Isocyclic Compounds
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ChemInform Abstract: Allyl Sulfide Synthesis of Phenylthio Migration: Relationship Between Stereochemistry of Starting Materials and Regioselectivity of Double Bond Formation.
First published: March 29, 1988
Abstract
Reduction of the phenylthio ketone (I) affords the syn- and anti-phenylthio alcohols (II) and (III).
ChemInform Abstract
Reduction of the phenylthio ketone (I) affords the syn- and anti-phenylthio alcohols (II) and (III). Phenylthio migration of each isomer preferentially leads to one of the two regioisomeric allylic sulfides (IV) and (V). Other examples are given; the regioselectivities of double bond formation and the E/Z selectivities of the formed allylic sulfides are affected by the substituents.
