Heterocyclic Compounds
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ChemInform Abstract: Synthesis and Pharmacological Study of Polyfunctional Macroheterocycles. Part 3. Synthesis and Antimicrobial Activity of Some Nitrogen- and Sulfur-Containing Macrocycles.
First published: January 12, 1988
Abstract
Reaction of the dimercaptothiadiazole (I) with the aziridine (II) gives the bisaminoethylmercapto derivative (III) which is cyclized with phthaloyl chloride (IV), forming the macrocyclic compound (V).
ChemInform Abstract
Reaction of the dimercaptothiadiazole (I) with the aziridine (II) gives the bisaminoethylmercapto derivative (III) which is cyclized with phthaloyl chloride (IV), forming the macrocyclic compound (V). This, the macrocycles (VI) and (VII) previously described, the open-chain compounds (VIII) and the complex of (VIIIa) with copper(II) acetate have antimicrobial activity.
