Heterocyclic Compounds
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ChemInform Abstract: Synthesis and Antiphlogistic Activity of Acyl-Substituted Benzoxa- and Benzodioxaheterocycles and Their Acyclic Analogues.
First published: January 12, 1988
Abstract
Friedel-Crafts acylation of the (cyclic) phenol ethers (I) gives the ketones (III).
ChemInform Abstract
Friedel-Crafts acylation of the (cyclic) phenol ethers (I) gives the ketones (III). The Mannich bases (VI) are prepared from the acetyl compounds (IIIa) - (IIIf) (R3: -Me). Some of the compounds synthesized have antiphlogistic activity but low toxicity.
