ChemInform Abstract: Ortho-Alkylation of o-, m- and p-Cresol by Cyclohexene in the Presence of Aluminum Cresolates.
Abstract
The reaction between p-cresol (I) and cyclohexene (II) in the presence of aluminum p-cresolate, molar ratio 3:1:0.1, affords the o-alkylation products (III) and (IV) as the main components along with minor amounts of ethers resulting from alkylation of the hydroxy group.
ChemInform Abstract
The reaction between p-cresol (I) and cyclohexene (II) in the presence of aluminum p-cresolate, molar ratio 3:1:0.1, affords the o-alkylation products (III) and (IV) as the main components along with minor amounts of ethers resulting from alkylation of the hydroxy group. The same reaction between (I), (II) and aluminum p-cresolate, but with a molar ratio of 1:4:0.3, gives the o,o'-dialkyl derivative (IV) as the main product. The reaction between o-cresol (V) and cyclohexene (II) in the presence of aluminum o-cresolate, molar ratio 3:1:0.9, gives the o-alkylation product (VI) as the main component along with minor amounts of m- and p-alkylation products and ethers. The reaction of m-cresol (VII), cyclohexene (II) and aluminum m-cresolate, molar ratio 3:1:0.3, gives a mixture of the o-alkylation products (VIII) and (IX) along with some minor components.
