Volume 18, Issue 44
Preparative Organic Chemistry
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ChemInform Abstract: Production of (R)-1-(1,3-Dithian-2-yl)propan-2-ol by Microbial Reduction.

R. BERNARDI

R. BERNARDI

Dip. Chim. Politec. Milano, CNR, I-20133 Milano, Italy

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R. CARDILLO

R. CARDILLO

Dip. Chim. Politec. Milano, CNR, I-20133 Milano, Italy

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D. GHIRINGHELLI

D. GHIRINGHELLI

Dip. Chim. Politec. Milano, CNR, I-20133 Milano, Italy

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O. VAJNA DE PAVA

O. VAJNA DE PAVA

Dip. Chim. Politec. Milano, CNR, I-20133 Milano, Italy

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First published: November 3, 1987

Abstract

The reduction of the carbonyl compounds (I) with Streptomyces species, Aspergillus niger and Geotrichum candidum is studied.

ChemInform Abstract

The reduction of the carbonyl compounds (I) with Streptomyces species, Aspergillus niger and Geotrichum candidum is studied. The production of the desired title compound from (Ia) can be achieved with high enantiomeric purity (99% e.e.) by reduction with a Streptomyces species.

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