Preparative Organic Chemistry
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ChemInform Abstract: Synthesis of N,O-Dimethylhydroxylamine Hydrochloride.
First published: September 22, 1987
Abstract
The N-methoxy-N-methylcarbamate (III) is prepared from the chloroformate (I) in a one-pot procedure by treatment with hydroxylamine hydrochloride and subsequent methylation of the N-ethoxycarbonylhydroxylamine (II) formed.
ChemInform Abstract
The N-methoxy-N-methylcarbamate (III) is prepared from the chloroformate (I) in a one-pot procedure by treatment with hydroxylamine hydrochloride and subsequent methylation of the N-ethoxycarbonylhydroxylamine (II) formed. The compound (III) undergoes saponification and decarboxylation, yielding the hydrochloride (IV) mentioned in the title. (IV) is a useful reagent, e.g. for the preparation of N-methoxymethylamides.
