Volume 18, Issue 35
Heterocyclic Compounds
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ChemInform Abstract: Pyrimidine Nucleoside Analogs. Part 20. Aminomethylation of 5-Fluorouracil and Thymine.

R. A. ZHUK

R. A. ZHUK

Inst. org. sinteza AN Latv. SSR, Riga 226006

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A. S. LUDZISHA

A. S. LUDZISHA

Inst. org. sinteza AN Latv. SSR, Riga 226006

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R. G. KOSTYANOVSKII

R. G. KOSTYANOVSKII

Inst. org. sinteza AN Latv. SSR, Riga 226006

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First published: September 1, 1987

ChemInform Abstract

The uracil derivatives (I) are aminomethylated to form the Mannich bases (IV) which are also obtained from the silyl ethers (V) and the formaldehyde O,N- (VI) or N,N-acetals (VII).

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