ChemInform Abstract: Synthesis and Hypotensive Activity of Benzopyran Derivatives.
Abstract
The hydroxy(propenyl)acetophenone (I) is transformed into the dihydrobenzopyranyl ethanolamines (VI) as shown in the reaction scheme.
ChemInform Abstract
The hydroxy(propenyl)acetophenone (I) is transformed into the dihydrobenzopyranyl ethanolamines (VI) as shown in the reaction scheme. These and the dihydrobenzopyrans (VII) and (VIII) also synthesized are tested for cardiovascular effects in anesthetized dogs. The hydroxynitroxyamines (VI) possess strong hypotensive and positive chronotropic activities.