Isocyclic Compounds
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ChemInform Abstract: Transition Metal Catalyzed Reaction of Me3SiCN. Part 4. Palladium-Catalyzed Cyanation of Aryl Halides by Trimethylsilyl Cyanide.
First published: June 16, 1987
Abstract
Reaction of the aryl iodides (I) with trimethylsilyl cyanide (II) in the presence of catalytic amounts of the palladium complex (III) yields the aryl cyanides (IV).
ChemInform Abstract
Reaction of the aryl iodides (I) with trimethylsilyl cyanide (II) in the presence of catalytic amounts of the palladium complex (III) yields the aryl cyanides (IV). The best results are obtained using triethylamine as the solvent. In the case of the bromoiodobenzene (Va), the dinitrile (VI) is formed, together with the bromonitrile (VIIa) as the main product, whereas the diiodobenzene (Vb) only produces (VI).
