ChemInform Abstract: Synthesis of a Proposed Antigenic Hexapeptide from Escherichia coli K88 Protein Fimbriae.
Abstract
The title hexapeptide (IX) is assembled by stepwise synthesis in solution (conventional methods) Starting from the units (IV) and (V) in an overall yield of 44%.
ChemInform Abstract
The title hexapeptide (IX) is assembled by stepwise synthesis in solution (conventional methods) Starting from the units (IV) and (V) in an overall yield of 44%. The Arg derivative (IV), in turn, is prepared with an improved yield by a novel one-pot procedure. - The synthetic peptide (IX) is coupled to bovine serum albumin and used in direct immunization of rabbits.