Current Awareness
Open Access
Current Awareness
First published: 31 May 2002
Abstract
In order to keep subscribers up-to-date with the latest developments in their field, this current awareness service is provided by John Wiley & Sons and contains newly-published material on comparative and functional genomics. Each bibliography is divided into 16 sections. 1 Reviews & symposia; 2 General; 3 Large-scale sequencing and mapping; 4 Genome evolution; 5 Comparative genomics; 6 Gene families and regulons; 7 Pharmacogenomics; 8 Large-scale mutagenesis programmes; 9 Functional complementation; 10 Transcriptomics; 11 Proteomics; 12 Protein structural genomics; 13 Metabolomics; 14 Genomic approaches to development; 15 Technological advances; 16 Bioinformatics. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted
Current Awareness
- 1. Reviews & symposia
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- (2001). Special issue: Protein expression in Down syndrome brain. J Neural Transm-Suppl
- (2001). Special issue on genetics and genomics in molecular medicine. Trends Mol Med 7,
- (2002). Special issue: The Molecular Biology Database Collection - 2002 update. Nucleic Acids Res 30,
- (2001). Special issue: Bioinformatics of Genome Regulation and Structure - August 7-11, 2000 - Novosibirsk, Russia. Mol Biol-Engl Tr 35,
- Aharoni A, Vorst O. (2002). DNA microarrays for functional plant genomics. Plant Mol Biol 48, 99
- Alam R, Gorska M. (2001). Genomic microarrays: Arraying order in biological chaos?. Am J Respir Cell Mol Biol 25, 405
- Bals R, Jany B. (2001). Identification of disease genes by expression profiling (Review). Eur Resp J 18, 882
- Bill RM. (2001). Yeast: A panacea for the structure-function analysis of membrane proteins? (Review). Curr Genet 40, 157
- Bubendorf L. (2001). High-throughput microarray technologies: From genomics to clinics. Eur Urol 40, 231
- Buysse JM. (2001). The role of genomics in antibacterial target discovery. Curr Med Chem 8, 1713
- Castresana J. (2001). Comparative genomics and bioenergetics (Review). Biochim Biophys Acta 1506, 147
- Chen W, Tang DZ, Suo JF, Zhang YS, Xue YB. (2001). Expressional profiling of genes related to pollination and fertilization in rice. C R Acad Sci Ser III-Vie 324, 1111
- Choudhary JS, Blackstock WP, Creasy DM, Cottrell JS. (2001). Matching peptide mass spectra to EST and genomic DNA databases (Review). Trends Biotechnol 19, S17
- Colebatch G, Trevaskis B, Udvardi M. (2002). Functional genomics: Tools of the trade (Review). New Phytol 153, 27
- Dacks JB, Doolittle WF. (2001). Reconstructing/deconstructing the earliest eukaryotes: How comparative genomics can help (Review). Cell 107, 419
- Dean NM. (2001). Functional genomics and target validation approaches using antisense oligonucleotide technology. Curr Opin Biotechnol 12, 622
- Dongre AR, Opiteck G, Cosand WL, Hefta SA. (2001). Proteomics in the post-genome age. Biopolymers 60, 206
- Donson J, Fang YW, Espiritu-Santo G, Xing WM, Salazar A, Miyamoto S, Armendarez V, Volkmuth W. (2002). Comprehensive gene expression analysis by transcript profiling. Plant Mol Biol 48, 75
- Engidawork E, Lubec G. (2001). Protein expression in Down syndrome brain (Review). Amino Acids 21, 331
- Famulok M, Blind M, Mayer G. (2001). Intramers as promising new tools in functional proteomics (Review). Chem Biol 8, 931
- Fiehn O. (2002). Metabolomics: The link between genotypes and phenotypes. Plant Mol Biol 48, 155
- Finkelstein D, Ewing R, Gollub J, Sterky F, Cherry JM, Somerville S. (2002). Microarray data quality analysis: Lessons from the AFGC project. Plant Mol Biol 48, 119
- Fountoulakis M. (2001). Proteomics: Current technologies and applications in neurological disorders and toxicology (Review). Amino Acids 21, 363
- Gabrielson E, Berg K, Anbazhagan R. (2001). Functional genomics, gene arrays, and the future of pathology (Review). Mod Pathol 14, 1294
- Goble C. (2001). The low down on e-science and grids for biology (Review). Comp Funct Genom 2, 365
- Grant SGN, Husi H. (2001). Proteomics of multiprotein complexes: Answering fundamental questions in neuroscience (Review). Trends Biotechnol 19, S49
- Griffin TJ, Aebersold R. (2001). Advances in proteome analysis by mass spectrometry (Mini-Review). J Biol Chem 276, 45497
- Griffin TJ, Goodlett DR, Aebersold R. (2001). Advances in proteome analysis by mass spectrometry. Curr Opin Biotechnol 12, 607
- Hanson IM. (2001). Mammalian homologues of the Drosophila eye specification genes. Semin Cell Dev Biol 12, 475
- Herbert BR, Harry JL, Packer NH, Gooley AA, Pedersen SK, Williams KL. (2001). What place for polyacrylamide in proteomics? (Review). Trends Biotechnol 19, S3
- Herrmann PC, Liotta LA, Petricoin EF. (2001). Cancer proteomics: The state of the art. Dis Marker 17, 49
- Ito T, Chiba T, Yoshida M. (2001). Exploring the protein interactome using comprehensive two-hybrid projects (Review). Trends Biotechnol 19, S23
- Janson CG, During MJ. (2001). Viral vectors as part of an integrated functional genomics program (Review). Genomics 78, 3
- Janson CG, McPhee SWJ, Leone P, Freese A, During MJ. (2001). Viral-based gene transfer to the mammalian CNS for functional genomic studies (Review). Trends Neurosci 24, 706
- Jhoti H. (2001). High-throughput structural proteomics using x-rays (Review). Trends Biotechnol 19, S67
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- Jiang LL, Tsubakihara M, Heinke MY, Yao M, Dunn MJ, Phillips W, Dos Remedios CG, Nosworthy NJ. (2001). Heart failure and apoptosis: Electrophoretic methods support data from micro- and macro-arrays. A critical review of genomics and proteomics (Review). Proteomics 1, 1481
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- Kato-Maeda M, Gao Q, Small PM. (2001). Microarray analysis of pathogens and their interaction with hosts (Review). Cell Microbiol 3, 713
- Kellam P. (2001). Post-genomic virology: The impact of bioinformatics, microarrays and proteomics on investigating host and pathogen interactions (Review). Rev Med Virol 11, 313
- Kersten B, Burkle L, Kuhn EJ, Giavalisco P, Konthur Z, Lueking A, Walter G, Eickhoff H, Schneider U. (2002). Large-scale plant proteomics. Plant Mol Biol 48, 133
- Ko MSH. (2001). Embryogenomics: Developmental biology meets genomics (Review). Trends Biotechnol 19, 511
- Kornblum HL, Geschwind DH. (2001). The use of representational difference analysis and cDNA microarrays in neural repair research. Restor Neurol Neurosci 18, 89
- Kratz E, Dugas JC, Ngai J. (2002). Odorant receptor gene regulation: Implications from genomic organization (Review). Trends Genet 18, 29
- Lorens JB, Sousa C, Bennett MK, Molineaux SM, Payan DG. (2001). The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics. Curr Opin Biotechnol 12, 613
- Macoska JA. (2002). The progressing clinical utility of DNA microarrays. CA Cancer J Clin 52, 50
- Maggio ET, Ramnarayan K. (2001). Recent developments in computational proteomics (Review). Drug Discov Today 6, 996
- Mahlknecht U, Ottmann OG, Hoelzer D. (2001). Far-Western based protein-protein interaction screening of high-density protein filter arrays (Mini-Review). J Biotechnol 88, 89
- Maine EM. (2001). RNAi as a tool for understanding germline development in Caenohabditis elegans: Uses and cautions (Review). Dev Biol 239, 177
- Marciano PG, Eberwine JH, Raghupathi R, McIntosh TK. (2001). The assessment of genomic alterations using DNA arrays following traumatic brain injury (Review). Restor Neurol Neurosci 18, 105
- Mehraban F, Tomlinson JE. (2001). Application of industrial scale genomics to discovery of therapeutic targets in heart failure (Review). Eur J Heart Fail 3, 641
- Mills DA. (2001). Mutagenesis in the post genomics era: Tools for generating insertional mutations in the lactic acid. Curr Opin Biotechnol 12, 503
- Mitchell-Olds T, Clauss MJ. (2002). Plant evolutionary genomics. Curr Opin Plant Biol 5, 74
- Moseley MA. (2001). Current trends in differential expression proteomics: Isotopically coded tags (Review). Trends Biotechnol 19, S10
- Nakanishi T, Oka T, Akagi T. (2001). Recent advances in DNA microarrays (Review). Acta Med Okayama 55, 319
- Natsume T, Nakayama H, Isobe T. (2001). BIA-MS-MS: Biomolecular interaction analysis for functional proteomics (Review). Trends Biotechnol 19, S28
- Orengo CA, Bray JE, Buchan DWA, Harrison A, Lee D, Pearl FMG, Sillitoe I, Todd AE, Thornton JM. (2002). The CATH protein family database: A resource for structural and functional annotation of genomes - Review. Proteomics 2, 11
- Pertea M, Salzberg SL. (2002). Computational gene finding in plants. Plant Mol Biol 48, 39
- Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W. (2001). Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review. JAMA 286, 2270
- Prozorov AA. (2001). Recombinational rearrangements in bacterial genome and bacterial adaptation to the environment (Review). Microbiology-Engl Tr 70, 501
- Puig O, Caspary F, Rigaut G, Rutz B, Bouveret E, Bragado-Nilsson E, Wilm M, Seraphin B. (2001). The tandem affinity purification (TAP) method: A general procedure of protein complex purification (Review). Methods 24, 218
- Rabilloud T. (2002). Two-dimensional gel electrophoresis in proteomics: Old, old fashioned, but it still climbs up the mountains - Review. Proteomics 2, 3
- Raetz EA, Moos PJ, Szabo A, Carroll WL. (2001). Gene expression profiling: Methods and clinical applications in oncology. Hematol Oncol Clin North Am 15, 911
- Regnier FE, Riggs L, Zhang R, Xiong L, Liu P, Chakraborty A, Seeley E, Sioma C, Thompson RA. (2002). Special feature: Perspective - Comparative proteomics based on stable isotope labeling and affinity selection. J Mass Spectrom 37, 133
- Rehm BHA. (2001). Bioinformatic tools for DNA/protein sequence analysis, functional assignment of genes and protein classification (Mini-Review). Appl Microbiol Biotechnol 57, 579
- Reiser L, Mueller LA, Rhee SY. (2002). Surviving in a sea of data: A survey of plant genome data resources and issues in building data management systems. Plant Mol Biol 48, 59
- Roberts JKM. (2002). Proteomics and a future generation of plant molecular biologists. Plant Mol Biol 48, 143
- Schmidt R. (2002). Plant genome evolution: Lessons from comparative genomics at the DNA level. Plant Mol Biol 48, 21
- Schrader M, Schulz-Knappe P. (2001). Peptidomics technologies for human body fluids (Review). Trends Biotechnol 19, S55
- Simpson RJ, Dorow DS. (2001). Cancer proteomics: From signaling networks to tumor markers (Review). Trends Biotechnol 19, S40
- Turecek F. (2002). Special feature: Perspective - Mass spectrometry in coupling with affinity capture-release and isotope-coded affinity tags for quantitative protein analysis. J Mass Spectrom 37, 1
- Turkewitz AP, Orias E, Kapler G. (2002). Functional genomics: The coming of age for Tetrahymena thermophila (Review). Trends Genet 18, 35
- Van der Vet P, Roosendaal HE, Geurts PATM. (2001). C2M: Configurable chemical middleware (Review). Comp Funct Genom 2, 371
- Walke DW, Han CS, Shaw J, Wann E, Zambrowicz B, Sands A. (2001). In vivo drug target discovery: Identifying the best targets from the genome. Curr Opin Biotechnol 12, 626
- Weir M, Swindells M, Overington J. (2001). Insights into protein function through large-scale computational analysis of sequence and structure (Review). Trends Biotechnol 19, S61
- Wu SH, Ramonell K, Gollub J, Somerville S. (2001). Plant gene expression profiling with DNA microarrays (Review). Plant Physiol Biochem 39, 917
- Ye RW, Wang T, Bedzyk L, Croker KM. (2001). Applications of DNA microarrays in microbial systems (Review). J Microbiol Methods 47, 257
- Zhou HH, Roy S, Schulman H, Natan MJ. (2001). Solution and chips arrays in protein profiling (Review). Trends Biotechnol 19, S34
- 3. Large-scale sequencing and mapping
- Barakat A, Szick-Miranda K, Chang IF, Guyot R, Blanc G, Cooke R, Delseny M, Bailey-Serres J. (2001). The organization of cytoplasmic ribosomal protein genes in the Arabidopsis genome. Plant Physiol 127, 398
- Fitz-Gibbon ST, Ladner H, Kim UJ, Stetter KO, Simon MI, Miller JH. (2002). Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum. Proc Natl Acad Sci U S A 99, 984
- Goodner B, Hinkle G, Gattung S, Miller N, Blanchard M, Qurollo B, Goldman BS, Cao YW, Askenazi M, Halling C, Mullin L, Houmiel K, Gordon J, Vaudin M, Iartchouk O, Epp A, Liu F, Wollam C, Allinger M, Doughty D, Scott C, Lappas C, Markelz B, Flanagan C, Crowell C, Gurson J, Lomo C, Sear C, Strub G, Cielo C, Slater S. (YR). Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58. Science 294, 2323
- Kaneko T, Nakamura Y, Wolk CP, Kuritz T, Sasamoto S, Watanabe A, Iriguchi M, Ishikawa A, Kawashima K, Kimura T, Kishida Y, Kohara M, Matsumoto M, Matsuno A, Muraki A, Nakazaki N, Shimpo S, Sugimoto M, Takazawa M, Yamada M, Yasuda M, Tabata S. (2001). Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp strain PCC 7120. DNA Res 8, 205
- McClelland M, Sanderson KE, Spieth J, Clifton SW, Latreille P, Courtney L, Porwollik S, Ali J, Dante M, Du FY, Hou S, Layman D, Leonard S, Nguyen C, Scott K, Holmes A, Grewal N, Mulvaney E, Ryan E, Sun H, Florea L, Miller W, Stoneking T, Nhan M, Waterston R, Wilson RK. (2001). Complete genome sequence of Salmonella enterica serovar typhimurium LT2. Nature 413, 852
- Myler PJ, Beverlely SM, Cruz AK, Dobson DE, Ivens AC, McDonagh O, Madhubala R, Martinez-Calvillo S, Ruiz JC, Saxena A, Sisk E, Sunkin SM, Worthey E, Yan S, Stuart KD. (2001). The Leishmania genome project: New insights into gene organization and function. Med Microbiol Immunol 190, 9
- Parkhill J, Dougan G, James KD, Thomson NR, Pickard D, Wain J, Churcher C, Mungall KL, Bentley SD, Holden MTG, Sebaihia M, Baker S, Basham D, Brooks K, Chillingworth T, Connerton P, Cronin A, Davis P, Davies RM, Dowd L, White N, Farrar J, Feltwell T, Hamlin N, Haque A, Hien TT, Holroyd S, Jagels K, Krogh A, Larsen TS, Leather S, Moule S, O'Gaora P,Parry C, Quail M, Rutherford K, Simmonds M, Skelton J, Stevens K, Whitehead S, Barrell BG. (2001). Complete genome sequence of a multiple resistant Salmonella enterica serovar typhi CT18. Nature 413, 848
- Shimizu T, Ohtani K, Hirakawa H, Oshima K, Yamashita A, Shiba T, Ogasawara N, Hattori M, Kuhara S, Hayashi H. (2002). Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater. Proc Natl Acad Sci U S A 99, 996
- Wood DW, Setubal JC, Kaul R, Monks DE, Kitajima JP, Okura VK, Chen L, Wood GE, Almeida NF, Woo L, Chen Y, Paulsen IT, Eisen JA, Karp PD, Bovee D, Chapman P, Clendenning J, Deatherage G, Gillet W, Grant C, Kutyavin T, Levy R, Li MJ, McClelland E, Palmieri A, Raymond C, Rouse G, Saenphimmachak C, Wu Z, Romero P, Gordon D, Zhang S, Yoo H, Tao Y, Biddle P, Jung M, Krespan W, Perry M, Gordon-Kamm B, Liao L, Kim S, Hendrick C, Zhao ZY, Dolan M, Chumley F, Tingey SV, Tomb JF, Gordon MP, Olson MV, Nester EW. (2001). The genome of the natural genetic engineer Agrobacterium tumefaciens C58. Science 294, 2317
- 4. Evolutionary genomics
- Bourque G, Pevzner PA. (2002). Genome-scale evolution: Reconstructing gene orders in the ancestral species. Genome Res 12, 26
- Broughton RE, Milam JE, Roe BA. (2001). The complete sequence of the zebrafish (Danio rerio) mitochondrial genome and evolutionary patterns in vertebrate mitochondrial DNA. Genome Res 11, 1958
- Fischer G, Neuveglise C, Durrens P, Gaillardin C, Dujon B. (2001). Evolution of gene order in the genomes of two related yeast species. Genome Res 11, 2009
- Kuhn G, Hijri M, Sanders IR. (2001). Evidence for the evolution of multiple genomes in arbuscular mycorrhizal fungi. Nature 414, 745
- Qian J, Luscombe NM, Gerstein M. (2001). Protein family and fold occurrence in genomes: Power-law behaviour and evolutionary model. J Mol Biol 313, 673
- Richly E, Kurth J, Leister D. (2002). Mode of amplification and reorganization of resistance genes during recent Arabidopsis thaliana evolution. Mol Biol Evol 19, 76
- Salemi M, Vandamme AM. (2002). Hepatitis C virus evolutionary patterns studied through analysis of full-genome sequences. J Mol Evol 54, 62
- Snel B, Bork P, Huynen MA. (2002). Genomes in flux: The evolution of archaeal and proteobacterial gene content. Genome Res 12, 17
- 5. Comparative genomics
- Bolshakov VN, Topalis P, Blass C, Kokoza E, Della'Torre A, Kafatos FC, Louis C. (2002). A comparative genomic analysis of two distant Diptera, the fruit fly, Drosophila melanogaster, and the malaria mosquito, Anopheles gambiae. Genome Res 12, 57
- Chen R, Bouck JB, Weinstock GM, Gibbs RA. (2001). Comparing vertebrate whole-genome shotgun reads to the human genome. Genome Res 11, 1807
- Ge ZM, Feng Y, White DA, Schauer DB, Fox JG. (2001). Genomic characterization of Helicobacter hepaticus: Ordered cosmid library and comparative sequence analysis. FEMS Microbiol Lett 204, 147
- Liu H, Sachidanadam R, Stein L. (2001). Comparative genomics between rice and Arabidopsis shows scant collinearity in gene order. Genome Res 11, 2020
- 6. Pathways, gene families and regulons
- Doerks T, Copley RR, Schultz J, Ponting CP, Bork P. (2002). Systematic identification of novel protein domain families associated with nuclear functions. Genome Res 12, 47
- Evertsz EM, Au-Young J, Ruvolo MV, Lim AC, Reynolds MA. (2001). Hybridization cross-reactivity within homologous gene families on glass cDNA microarrays. Biotechniques 31, 1182
- Jackson RM, Russell RB. (2001). Predicting function from structure: Examples of the serine protease inhibitor canonical loop conformation found in extracellular proteins. Comput Chem 26, 31
- Li XM, Novotna J, Vohradsky J, Weiser J. (2001). Major proteins related to chlortetracycline biosynthesis in a Streptomyces aureofaciens production strain studied by quantitative proteomics. Appl Microbiol Biotechnol 57, 717
- Van Rossum AJ, Brophy PM, Tait A, Barrett J, Jefferies JR. (2001). Proteomic identification of glutathione S-transferases from the model nematode Caenorhabditis elegans. Proteomics 1, 1463
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- Yanagida M, Shimamoto A, Nishikawa K, Furuichi Y, Isobe T, Takahashi N. (2001). Isolation and proteomic characterization of the major proteins of the nucleolin-binding ribonucleoprotein complexes. Proteomics 1, 1390
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- 7. Pharmacogenomics
- Ahr A, Karn T, Solbach C, Seiter T, Strebhardt K, Holtrich U, Kaufmann M. (2002). Identification of high risk breast-cancer patients by gene expression profiling. Lancet 359, 131
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- Bezchlibnyk YB, Wang JF, McQueen GM, Young LT. (2001). Gene expression differences in bipolar disorder revealed by cDNA array analysis of post-mortem frontal cortex. J Neurochem 79, 826
- Blakely RD. (2001). Physiological genomics of antidepressant targets: Keeping the periphery in mind. J Neurosci 21, 8319
- Boer JM, Huber WK, Sultmann H, Wilmer F, Von Heydebreck A, Haas S, Korn B, Gunawan B, Vente A, Fuzesi L, Vingron M, Poustka A. (2001). Identification and classification of differentially expressed genes in renal cell carcinoma by expression profiling on a global human 31,5000-element cDNA array. Genome Res 11, 1861
- Caballero OL, De Souza SJ, Brentani RR, Simpson AJG. (2001). Alternative spliced transcripts as cancer markers. Dis Marker 17, 67
- Chen YD, Yakhini Z, Ben Dor A, Dougherty E, Trent JM, Bittner M. (2001). Analysis of expression patterns: The scope of the problem, the problem of scope. Dis Marker 17, 59
- Cole J, Tsou R, Wallace K, Gibran N, Isik F. (2001). Early gene expression profile of human skin to injury using high-density cDNA microarrays. Wound Repair Regen 9, 360
- Cortesini NSF, Piazza F, Ho E, Ciubotariu R, Le Maoult J, Dalla Favera R, Cortesini R. (2001). Distinct mRNA microarray profiles of tolerogenic dendritic cells. Hum Immunol 62, 1065
- Cox JM, Clayton CL, Tomita T, Wallace DM, Robinson PA, Crabtree JE. (2001). cDNA array analysis of cag pathogenicity island-associated Helicobacter pylori epithelial cell response genes. Infect Immun 69, 6970
- Friess H, Ding JY, Kleeff J, Liao Q, Berberat PO, Hammer J, Buchler MW. (2001). Identification of disease-specific genes in chronic pancreatitis using DNA array technology. Ann Surg 234, 769
- Fuller GN, Hess KR, Rhee CH, Yung WKA, Sawaya RA, Bruner JM, Zhang W. (2002). Molecular classification of human diffuse gliomas by multidimensional scaling analysis of gene expression profiles parallels morphology-based classification, correlates with survival, and reveals clinically-relevant novel glioma subsets. Brain Pathol 12, 108
- Gebauer M, Von Melchner H, Beckers T. (2001). Genomewide trapping of genes that encode secreted and transmembrane proteins repressed by oncogenic signaling. Genome Res 11, 1871
- Guillonneau F, Labas V, Auvin C, Praseuth D. (2001). A reliable and simple method for two-dimensional electrophoresis and identification of HeLa nuclear alkaline nucleic acid-binding proteins using immobilized pH gradient. Electrophoresis 22, 4391
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- Hurko O. (2001). Genetics and genomics in neuropsychopharmacology: The impact on drug discovery and development. Eur Neuropsychopharmacol 11, 491
- Jhaveri MS, Wagner C, Trepel JB. (2001). Impact of extracellular folate levels on global gene expression. Mol Pharmacol 60, 1288
- Joachimiak MP, Chang C, Rosenthal PJ, Cohen FE. (2001). The impact of whole genome sequence data on drug discovery: A malaria case study. Mol Med 7, 698
- Jun AS, Liu SH, Koo EH, Do DV, Stark WJ, Gottsch JD. (2001). Microarray analysis of gene expression in human donor corneas. Arch Ophthalmol 119, 1629
- Katsuma S, Nishi K, Tanigawara K, Ikawa H, Shiojima S, Takagaki K, Kaminishi Y, Suzuki Y, Hirasawa A, Ohgi T, Yano J, Murakami Y, Tsujimoto G. (2001). Molecular monitoring of bleomycin-induced pulmonary fibrosis by cDNA micro array-based gene expression profiling. Biochem Biophys Res Commun 288, 747
- Locklin RM, Riggs BL, Hicok KC, Horton HF, Byrne MC, Khosla S. (2001). Assessment of gene regulation by bone morphogenetic protein 2 in human marrow stromal cells using gene array technology. J Bone Miner Res 16, 2192
- Loring JF, Wen X, Lee JM, Seilhamer J, Somogyi R. (2001). A gene expression profile of Alzheimer's disease. DNA Cell Biol 20, 683
- Los G, Yang F, Samimi G, Manorek G, Guerorguieva IM, Howell S, Van Erp N, Breaux JK. (2002). Using mRNA expression profiling to determine anticancer drug efficacy. Cytometry 47, 66
- Manderson EN, Mes-Masson AM, Novak J, Lee PD, Provencher D, Hudson TJ, Tonin PN. (2002). Expression profiles of 290 ESTs mapped to chromosome 3 in human epithelial ovarian cancer cell lines using DNA expression oligonucleotide microarrays. Genome Res 12, 112
- Matejuk A, Dwyer J, Zamora A, Vandenbark AA, Offner H. (2002). Evaluation of the effects of 17β-estradiol (17β-E2) on gene expression in experimental autoimmune encephalomyelitis using DNA microarray. Endocrinology 143, 313
- Nakeff A, Sahay N, Pisano M, Subramanian B. (2002). Painting with a molecular brush: Genomic/proteomic interfacing to define the drug action profile of novel solid-tumor selective anticancer agents. Cytometry 47, 72
- Ngimbous BB, Bourgeois F, Mas C, Simonneau M, Moalic JM. (2001). Heart transplantation changes the expression of distinct gene families. Physiol Genomics 7, 115
- Oriola J, Halperin I, Mallofre C, Muntane J, Angel M, Rivera-Fillat F. (2001). Screening of selected genomic areas potentially involved in thyroid neoplasms. Eur J Cancer 37, 2470
- Park KS, Cho SY, Kim H, Paik YK. (2002). Proteomic alterations of the variants of human aldehyde dehydrogenase isozymes correlate with hepatocellular carcinoma. Int J Cancer 97, 261
- Pasinetti GM, Ho L. (2001). From cDNA microarrays to high-throughput proteomics. Implications in the search for preventive initiatives to slow the clinical progression of Alzheimer's disease dementia. Restor Neurol Neurosci 18, 137
- Poon TCW, Johnson PJ. (2001). Proteome analysis and its impact on the discovery of serological tumor markers. Clin Chim Acta 313, 231
- Rae JM, Johnson MD, Lippman ME, Flockhart DA. (2001). Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: Studies with cDNA and oligonucleotide expression arrays. J Pharmacol Exp Ther 299, 849
- Ramaswamy S, Tamayo P, Rifkin R, Mukherjee S, Yeang CH, Angelo M, Ladd C, Reich M, Latulippe E, Mesirov JP, Poggio T, Gerald W, Loda M, Lander ES, Golub TR. (2001). Multiclass cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci U S A 98, 15149
- Rigolet M, Faussillon M, Baudry D, Junien C, Jeanpierre C. (2001). Profiling of differential gene expression in Wilms tumor by cDNA expression array. Pediatr Nephrol 16, 1113
- Rooney PH, Boonsong A, McKay JA, Marsh S, Stevenson DAJ, Murray GI, Curran S, Haites NE, Cassidy K, McLeod HL. (2001). Colorectal cancer genomics: Evidence for multiple genotypes which influence survival. Br J Cancer 85, 1492
- Rosenberger CM, Pollard AJ, Finlay BB. (2001). Gene array technology to determine host responses to Salmonella. Microbes Infect 3, 1353
- Ross DT, Perou CM. (2001). A comparison of gene expression signatures from breast tumors and breast tissue derived cell lines. Dis Marker 17, 99
- Rybicki BA, Iyengar SK, Harris T, Liptak R, Elston RC, Maliarik MJ, Iannuzzi MC. (2002). Prospects of admixture linkage disequilibrium mapping in the African-American genome. Cytometry 47, 63
- Schonberger SJ, Edgar PF, Kydd R, Faull RLM, Cooper GJS. (2001). Proteomic analysis of the brain in Alzheimer's disease: Molecular phenotype of a complex disease process. Proteomics 1, 1519
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- Sibille E, Hen R. (2001). Combining genetic and genomic approaches to study mood disorders. Eur Neuropsychopharmacol 11, 413
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- 9. Functional genomics
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- 10. Transcriptomics
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- 11. Proteomics
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- 16. Bioinformatics
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