Mahkota Dewa Subcritical Water Extraction Process: Experimental and Molecular Dynamics Simulation Study
Nurmaryam Aini Hashim
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorCorresponding Author
Siti Kholijah Abdul Mudalip
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Universiti Malaysia Pahang, Centre of Excellence for Advanced Research in Fluid Flow (CARiFF), Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Correspondence: Siti Kholijah Abdul Mudalip ([email protected]), Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia.Search for more papers by this authorNoorlisa Harun
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorRohaida Che Man
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorSiti Zubaidah Sulaiman
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorZatul Iffah Mohd Arshad
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorShalyda M. Shaarani
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorJannatul Azmir
Monash University, ARC Industrial Transformation Research Hub for Computational, Particle Technology, Department of Chemical Engineering, Welington Road, 3800 Clayton, VIC, Australia
Search for more papers by this authorNurmaryam Aini Hashim
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorCorresponding Author
Siti Kholijah Abdul Mudalip
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Universiti Malaysia Pahang, Centre of Excellence for Advanced Research in Fluid Flow (CARiFF), Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Correspondence: Siti Kholijah Abdul Mudalip ([email protected]), Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia.Search for more papers by this authorNoorlisa Harun
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorRohaida Che Man
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorSiti Zubaidah Sulaiman
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorZatul Iffah Mohd Arshad
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorShalyda M. Shaarani
Universiti Malaysia Pahang, Faculty of Chemical & Natural Resources Engineering, Lebuh Raya Tun Razak, 26300 Gambang, Pahang, Malaysia
Search for more papers by this authorJannatul Azmir
Monash University, ARC Industrial Transformation Research Hub for Computational, Particle Technology, Department of Chemical Engineering, Welington Road, 3800 Clayton, VIC, Australia
Search for more papers by this authorAbstract
Subcritical water extraction and molecular dynamics simulation were performed to investigate mangiferin and antioxidant extraction from Mahkota Dewa fruits at different operating temperatures. The mangiferin yield and antioxidant activity were analyzed using high-performance liquid chromatography and 2-diphenyl-1-picrylhydrazyl assay method, respectively. The diffusivity and intermolecular interactions were determined by mean squared displacement (MSD) and radial distribution function (RDF) analysis, respectively. The temperature exerts a momentous effect on mangiferin yield and antioxidant activity of the extract. The MSD result showed an increment in diffusivity coefficient of mangiferin with temperature. The RDF analysis revealed hydrogen bonding formations between mangiferin and water through OH2O••HMR4(OH1) interaction that plays a role in the extraction process.
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