Volume 101, Issue 3 pp. 592-595
CASE REPORT

Suicide left ventricle following protamine: A case report

Saliha Erdem MD

Saliha Erdem MD

Department of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas Health Science Center at Houston, Houston, Texas, USA

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Sin Yeong An MD

Sin Yeong An MD

Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA

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Courtney A. McAlister RN, BSN

Courtney A. McAlister RN, BSN

Department of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas Health Science Center at Houston, Houston, Texas, USA

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Sukhdeep S. Basra MD

Corresponding Author

Sukhdeep S. Basra MD

Department of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas Health Science Center at Houston, Houston, Texas, USA

Correspondence Sukhdeep S. Basra, MD, 6400 Fannin, Ste 2350, Houston, TX 77030, USA.

Email: [email protected]

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First published: 10 January 2023
Citations: 1

Abstract

A patient with severe aortic stenosis and left ventricular hypertrophy underwent a transcatheter aortic valve replacement. The patient's blood pressure significantly dropped after protamine administration. A diagnosis of suicide left ventricle post-valve replacement was made. The diagnosis and management of the protamine reaction are detailed. This case highlights the need to slowly infuse protamine sulfate and monitor for adverse events.

CONFLICTS OF INTEREST

SB has consulted for AstraZeneca Pharmaceuticals and received travel support from Abbott Laboratories, Edwards Lifesciences, AstraZeneca Pharmaceuticals, and Boston Scientific. There are no other relationships with industry or competing interests to disclose.

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