Data are data: Do we need a randomized trial of transcatheter aortic valve replacement for bicuspid valves?
Key Points
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No randomized trials have been done for TAVR in bicuspid aortic valve (BAV) and probably will never be done.
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TAVR for BAV has a similar risk profile to tricuspid aortic valve patients except for a higher risk of permanent pacemaker implantation at 30 and 180 days after the index procedure.
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Further real-world data are needed to refine patient selection, procedural technique, and lifetime planning of intervention.