Ionic Liquids as Extractor Agents and Reaction Media in Ester Synthesis
Corresponding Author
Francisco José Hernández Fernández
Department of Chemical and Environmental Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, Technical University of Cartagena, Campus La Muralla, 30202 Cartagena, Murcia, Spain.
Department of Chemical and Environmental Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, Technical University of Cartagena, Campus La Muralla, 30202 Cartagena, Murcia, Spain.Search for more papers by this authorAntonia Pérez de los Ríos
Department of Chemical Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, University of Murcia, Campus de Espinardo, 30100 Murcia, Spain.
Search for more papers by this authorJoaquín Quesada-Medina
Department of Chemical Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, University of Murcia, Campus de Espinardo, 30100 Murcia, Spain.
Search for more papers by this authorSergio Sánchez-Segado
Department of Chemical and Environmental Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, Technical University of Cartagena, Campus La Muralla, 30202 Cartagena, Murcia, Spain.
Search for more papers by this authorCorresponding Author
Francisco José Hernández Fernández
Department of Chemical and Environmental Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, Technical University of Cartagena, Campus La Muralla, 30202 Cartagena, Murcia, Spain.
Department of Chemical and Environmental Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, Technical University of Cartagena, Campus La Muralla, 30202 Cartagena, Murcia, Spain.Search for more papers by this authorAntonia Pérez de los Ríos
Department of Chemical Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, University of Murcia, Campus de Espinardo, 30100 Murcia, Spain.
Search for more papers by this authorJoaquín Quesada-Medina
Department of Chemical Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, University of Murcia, Campus de Espinardo, 30100 Murcia, Spain.
Search for more papers by this authorSergio Sánchez-Segado
Department of Chemical and Environmental Engineering, Regional Campus of International Excellence “Campus Mare Nostrum”, Technical University of Cartagena, Campus La Muralla, 30202 Cartagena, Murcia, Spain.
Search for more papers by this authorAbstract
During the last decade, ionic liquids technology has received growing attention due to the advantages they offer with respect to organic solvents. Although, in many cases, ionic liquids have simply been used to replace organic solvents, mainly due to their lack of vapor pressure, they have often led to improve process. In this work, the focus is on the application of ionic liquid technology as reaction media in the enzymatic synthesis of esters and also as extractor agents in the separation of reaction mixtures in the synthesis of esters. As reaction media, ionic liquids are opening up new fields in nonaqueous enzymology. The advantages of using ionic liquids over the use of organic solvents as reaction medium for biocatalysis include enhancement of enzyme activity, stability and selectivity. In this work, the effect of the nature of the ionic liquid on activity, selectivity, and stability of enzymes which catalyze esters synthesis has been carefully analyzed. The use of ionic liquids as extraction agent is also overviewed. Specifically, liquid-liquid extraction using ionic liquids and supported liquid membranes based on ionic liquids have been studied.
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