Volume 14, Issue 11 e1700266
Full Paper

Chaetochromones A – C, Three New Polyketides from Mangrove Plant Derived Endophytic Fungus Phomopsis sp. SCSIO 41006

Zhi-Ran Ju

Zhi-Ran Ju

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301 P. R. China

Department of Chemistry, Jinan University, Guangzhou, 510632 P. R. China

These authors contributed equally to this work.Search for more papers by this author
Xiu-Ping Lin

Xiu-Ping Lin

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301 P. R. China

These authors contributed equally to this work.Search for more papers by this author
Minke Li

Minke Li

Drug Discovery Pipeline/Guangdong Provincial Key Laboratory of Biocomputing, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530 P. R. China

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Ying Wang

Ying Wang

Department of Chemistry, Jinan University, Guangzhou, 510632 P. R. China

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Yong-Qi Tian

Yong-Qi Tian

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301 P. R. China

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Jun-Feng Wang

Jun-Feng Wang

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301 P. R. China

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Juan Liu

Juan Liu

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301 P. R. China

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Zhengchao Tu

Zhengchao Tu

Drug Discovery Pipeline/Guangdong Provincial Key Laboratory of Biocomputing, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530 P. R. China

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Shi-Hai Xu

Shi-Hai Xu

Department of Chemistry, Jinan University, Guangzhou, 510632 P. R. China

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Yonghong Liu

Yonghong Liu

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301 P. R. China

University of Chinese Academy of Sciences, Beijing, 100049 P. R. China

South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangzhou, 510006 P. R. China

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First published: 10 August 2017
Citations: 6

Abstract

Three new polyketides, chaetochromones A – C (1 – 3), together with a chromone (4), were isolated from the ethyl acetate extract of mangrove-derived fungus Phomopsis sp. SCSIO 41006. Their structures were elucidated by means of spectroscopic techniques (UV, IR, MS, 1D- and 2D-NMR). The absolute configurations of the new compounds were established by CD data.

Graphical Abstract

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