Volume 13, Issue 11 pp. 1469-1474
Full Paper

Chemical Constituents from the Stems of Daphne holosericea (Diels) Hamaya

Qing-Yun Ma

Qing-Yun Ma

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101 P. R. China

These authors contributed equally to this work.Search for more papers by this author
Yi-Chun Chen

Yi-Chun Chen

College of Forestry, Southwest Forestry University, Kunming, 650224 P. R. China

These authors contributed equally to this work.Search for more papers by this author
Sheng-Zhuo Huang

Sheng-Zhuo Huang

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101 P. R. China

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Fan-Dong Kong

Fan-Dong Kong

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101 P. R. China

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Li-Man Zhou

Li-Man Zhou

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101 P. R. China

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Hao-Fu Dai

Hao-Fu Dai

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101 P. R. China

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Yan Hua

Yan Hua

College of Forestry, Southwest Forestry University, Kunming, 650224 P. R. China

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You-Xing Zhao

You-Xing Zhao

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101 P. R. China

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First published: 23 July 2016
Citations: 9

Abstract

Two new compounds, one flavanol dimer dapholosericol A (1) and one tigliane diterpene dapholosericin A (2), together with ten known ones, were isolated from the AcOEt extract of Daphne holosericea (Diels) Hamaya. Their structures were elucidated by their spectroscopic data analysis. Compounds 1 and 2 showed moderate activities against acetylcholinesterase with inhibition ratio of 36% and 29% at a concentration of 100 μmol/l, respectively.

Graphical Abstract

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