Research Article

Limonoids with an Oxygen Bridge between C(1) and C(29) from the Seeds of a Krishna Mangrove, Xylocarpus granatum

Corresponding Author

Min-Yi Li

[email protected]

Marine Drugs Research Center, College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, P. R. China (phone: +86-20-85222377; fax: +86-20-85224766)

Marine Drugs Research Center, College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, P. R. China (phone: +86-20-85222377; fax: +86-20-85224766)Search for more papers by this author

Qiang Xiao,

Qiang Xiao

Institute of Organic Chemistry, Jiangxi Science & Technology Normal University, Nanchang 330013, P. R. China

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Tirumani Satyanandamurty,

Tirumani Satyanandamurty

Government Degree College at Amadala valasa, Srikakulam District, Andhra Pradesh 532185, India

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Jun Wu,

Corresponding Author

Jun Wu

[email protected]

Marine Drugs Research Center, College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, P. R. China (phone: +86-20-85222377; fax: +86-20-85224766)

Min-Yi Li,

Corresponding Author

Min-Yi Li

[email protected]

Marine Drugs Research Center, College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, P. R. China (phone: +86-20-85222377; fax: +86-20-85224766)

Qiang Xiao,

Qiang Xiao

Institute of Organic Chemistry, Jiangxi Science & Technology Normal University, Nanchang 330013, P. R. China

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Tirumani Satyanandamurty,

Tirumani Satyanandamurty

Government Degree College at Amadala valasa, Srikakulam District, Andhra Pradesh 532185, India

Search for more papers by this author

Jun Wu,

Corresponding Author

Jun Wu

[email protected]

Marine Drugs Research Center, College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, P. R. China (phone: +86-20-85222377; fax: +86-20-85224766)

First published: 13 February 2014

https://doi.org/10.1002/cbdv.201300057

Citations: 15

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Abstract

Ten limonoids, named granatumins L–U (1–10, resp.), were isolated from the seeds of an Indian mangrove, Xylocarpus granatum, collected in the estuary of Krishna, Andhra Pradesh. The structures of these compounds were established on the basis of spectroscopic data. The relative configuration of granatumin L (1) was confirmed by a single-crystal X-ray diffraction analysis. Granatumins L–T (1–9, resp.) belong to the small group of limonoids with an oxygen bridge between C(1) and C(29), while granatumin U (10) is a 28-Me-oxidized mexicanolide. This is the first report of limonoids with an O-bridge between C(1) and C(29) from the Indian X. granatum. The pronounced structural diversity of limonoids from this mangrove might originate from environmental factors.

Graphical Abstract

References

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Volume11, Issue2

February 2014

Pages 262-275

Limonoids with an Oxygen Bridge between C(1) and C(29) from the Seeds of a Krishna Mangrove, Xylocarpus granatum

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Limonoids with an Oxygen Bridge between C(1) and C(29) from the Seeds of a Krishna Mangrove, Xylocarpus granatum

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