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Conformational behavior of the polysaccharide backbone of murein
B. Leps,
H. Labischinski,
H. Bradaczek,
B. Leps
Institute of Crystallography, Free University of Berlin, D-1000 Berlin 33, Takustrasse 6
Search for more papers by this authorCorresponding Author
H. Labischinski
Robert Koch-Institute of the Federal Health Office, Berlin, D-1000 Berlin 65, Nordufer 20
Robert Koch-Institute of the Federal Health Office, Berlin, D-1000 Berlin 65, Nordufer 20, F.R.G.Search for more papers by this authorH. Bradaczek
Institute of Crystallography, Free University of Berlin, D-1000 Berlin 33, Takustrasse 6, F.R.G.
Search for more papers by this authorB. Leps,
H. Labischinski,
H. Bradaczek,
B. Leps
Institute of Crystallography, Free University of Berlin, D-1000 Berlin 33, Takustrasse 6
Search for more papers by this authorCorresponding Author
H. Labischinski
Robert Koch-Institute of the Federal Health Office, Berlin, D-1000 Berlin 65, Nordufer 20
Robert Koch-Institute of the Federal Health Office, Berlin, D-1000 Berlin 65, Nordufer 20, F.R.G.Search for more papers by this authorH. Bradaczek
Institute of Crystallography, Free University of Berlin, D-1000 Berlin 33, Takustrasse 6, F.R.G.
Search for more papers by this authorAbstract
The energetically possible conformations for the alternating heteropolysaccharide backbone of murein, consisting of N-acetylglucosamine and N-acetylmuramic acid, were calculated using an empirical approach. The calculations were carried out for regular as well as for random-chain polymers, resulting in a model for the saccharide strands featuring extended chains with a length increment of 0.98–1.02 nm per disaccharide unit and peptide attachment sites at every second saccharide residuum pointing into all directions with propagation angles of 80–100° between consecutive sites.
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