Editorial
Plasticity of hematopoietic stem cells: Enough to induce tolerance and repair tissue?
Richard K. Burt,
Ann E. Traynor,
Yu Oyama,
Walter G. Barr,
Corresponding Author
Richard K. Burt
Northwestern University Medical Center, Chicago, Illinois
Division of Immune Therapy and Autoimmune Disease, Northwestern University Medical Center, Chicago, IL 60611Search for more papers by this authorAnn E. Traynor
Northwestern University Medical Center, Chicago, Illinois
Search for more papers by this authorYu Oyama
Northwestern University Medical Center, Chicago, Illinois
Search for more papers by this authorWalter G. Barr
Northwestern University Medical Center, Chicago, Illinois
Search for more papers by this authorRichard K. Burt,
Ann E. Traynor,
Yu Oyama,
Walter G. Barr,
Corresponding Author
Richard K. Burt
Northwestern University Medical Center, Chicago, Illinois
Division of Immune Therapy and Autoimmune Disease, Northwestern University Medical Center, Chicago, IL 60611Search for more papers by this authorAnn E. Traynor
Northwestern University Medical Center, Chicago, Illinois
Search for more papers by this authorYu Oyama
Northwestern University Medical Center, Chicago, Illinois
Search for more papers by this authorWalter G. Barr
Northwestern University Medical Center, Chicago, Illinois
Search for more papers by this author
REFERENCES
- 1 Billingham R, Brent L, Medwar P. Actively acquired tolerance of foreign cells. Nature 1953; 1972: 603.
- 2 Weissman IL. Transfer of tolerance. Transplantation 1973; 15: 265–9.
- 3 Slavin S, Strober S, Fuks Z, Kaplan HS. Induction of specific tissue transplantation tolerance using fractionated total body irradiation in adult mice: long term survival of allogeneic bone marrow and skin grafts. J Exp Med 1977; 146: 34–48.
- 4 Ildstad ST, Sachs DH. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature 1984; 307: 168–70.
- 5 Nakamura T, Good RA, Yasumizu R, Inoue S, Oo MM, Hamashima Y, et al. Successful liver allografts in mice by combination with allogeneic bone marrow transplantation. Proc Natl Acad Sci U S A 1986: 83: 4529–32.
- 6 Burt RK. BMT for severe autoimmune diseases: an idea whose time has come. Oncology (Huntingt) 1997; 11: 1001–14.
- 7 Burt RK, Padilla J, Begolka WS, Canto MC, Miller SD. Effect of disease stage on clinical outcome after syngeneic bone marrow transplantation for relapsing experimental autoimmune encephalomyelitis. Blood 1998: 91: 2609–16.
- 8 Kamiya M, Sohen S, Yamane T, Tanaka S. Effective treatment of mice with type II collagen induced arthritis with lethal irradiation and bone marrow transplantation. J Rheumatol 1993; 20: 225–30.
- 9 Pestronk A. Drachman DB. Teoh R. Adams RN. Combined short-term immunotherapy for experimental autoimmune myasthenia gravis. Ann Neurol 1983; 14: 235–41.
- 10 Van Bekkum DW, Bohre EP, Houben PF, Knaan-Shanzer S. Regression of adjuvant-induced arthritis in rats following bone marrow transplantation. Proc Natl Acad Sci U S A 1989; 86: 10090–4.
- 11 Ikehara S, Ohtsuki H, Good RA, Asamoto H, Nakamura T, Sekita K, et al. Prevention of type I diabetes in nonobese diabetic mice by allogenic bone marrow transplantation. Proc Natl Acad Sci U S A 1985; 82: 7743–7.
- 12 Ikehara S, Good RA, Nakamura T, Sekita K, Inoue S, Oo MM, et al. Rationale for bone marrow transplantation in the treatment of autoimmune diseases. Proc Natl Acad Sci U S A 1985; 82: 2483–7.
- 13 Hawkes CH. Twin studies in medicine—what do they tell us? QJM 1997; 90: 311–21.
- 14 Lowenthal RM, Cohen ML, Atkinson K, Biggs JC. Apparent cure of rheumatoid arthritis following bone marrow transplantation. J Rheumatol 1993; 20: 137–40.
- 15 Slavin S. Treatment of life-threatening autoimmune diseases with myeloablative doses of immunosuppressive agents: experimental background and rationale for ABMT. Bone Marrow Transplant 1993; 12: 85–8.
- 16 Brodsky RA, Petri M, Smith BD, Steifter J, Spivak JL, Styler M, et al. Immunablative high dose cyclophosphamide without stem cell rescue for refractory severe autoimmune disease. Ann Intern Med 1998; 129: 1031–5.
- 17 Joske DJ, Ma DT, Langlands DR, Owen ET. Autologous bone-marrow transplantation for rheumatoid arthritis [letter]. Lancet 1997; 350: 337.
- 18 Burt RK, Georganas C, Schroeder J, Traynor A, Stefka J, Schuening F, et al. Autologous hematopoietic stem cell transplantation in refractory rheumatoid arthritis: sustained response in two of four patients. Arthritis Rheum 1999: 42: 2281–5.
- 19 Snowden JA, Biggs JC, Milliken ST, Fuller A, Brooks PM. A phase I/II dose escalation study of intensified cyclophosphamide and autologous blood stem cell rescue in severe, active rheumatoid arthritis. Arthritis Rheum 1999; 42: 2286–92.
- 20 Burt RK, Barr W, Oyama Y, Traynor A, Slavin S. Future strategies in hematopoietic stem cell transplantation for rheumatoid arthritis. J Rheumatol 2001; 28 Suppl 64: 42–8.
- 21
Wulffraat N,
van Royen A,
Bierings M,
Vossen J,
Kuis W.
Autologous haemopoietic stem-cell transplantation in four patients with refractory juvenile chronic arthritis.
Lancet
1999;
353:
550–3.
10.1016/S0140-6736(98)05399-9 Google Scholar
- 22 Brinkman DMC, Smeets TJM, Kraan MC, ten Cate R, Vossen JM, Tak PP. Decrease in synovial cellularity and cytokine expression after autologous stem cell transplantation (ASCT) in patients with juvenile idiopathic arthritis (JIA). Arthritis Rheum 2002; 4: 1121–2.
- 23 Burt RK, Brenner M, Burns W, Courier E, Firestein G, Hahn B, et al. Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease. J Clin Immunol 2000; 20: 1–9.
- 24 Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R, et al. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 2001; 105: 369–77.
- 25 Lagasse E, Connors H, Al-Dhalimy M, Reitsma M, Dohse M, Osborne L, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000; 6: 1229–34.
- 26 Petersen BE, Bowen WC, Patrene KD, Mars WM, Sullivan AK, Murase N, et al. Bone marrow as a potential source of hepatic oval cells. Science 1999; 284: 1168–70.
- 27 Mezey E, Chandross KJ, Harta G, Maki RA, McKercher SR. Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 2000; 290: 1779–82.
- 28 Alison MR, Poulsom R, Jeffery R, Dhillon AP, Quaglia A, Jacob J, et al. Hepatocytes from non-hepatic adult stem cells. Nature 2000; 406: 257.
