N1-Hetaryl Substituted Pyridine- and Pyrazinecarboxamidrazones with Antimycobacterial Activity†
Dedicated to Prof. Dr. W. Wiegreb on the occasion of his 65th birthday.
Abstract
A series of amidrazones was prepared and characterized by 1H NMR and mass spectroscopy. The substances were tested against M. tuberculosis, M. avium, M. intracellulare, and M. lufu. Compounds 11–13 exhibit a satisfactory inhibition of mycobacteria.