Synthesis of elastin-based polymer and evaluation of its intermolecular interactions with hydroxypropyl methylcellulose
Corresponding Author
B. Mahesh
Department of Chemistry, JSS Academy of Technical Education, Bengaluru, 560 060 Karnataka, India
Correspondence to: B. Mahesh (E-mail: [email protected])Search for more papers by this authorG. S. Nanjundaswamy
Department of Chemistry, JSS Academy of Technical Education, Bengaluru, 560 060 Karnataka, India
Search for more papers by this authorD. Channe Gowda
Department of Studies in Chemistry, Manasagangotri, University of Mysore, Mysuru, 570 006 Karnataka, India
Search for more papers by this authorB. Siddaramaiah
Department of Polymer Science and Technology, Sri Jayachamarajendra College of Engineering, JSS Science & Technology University, Mysuru, 570 006 Karnataka, India
Search for more papers by this authorCorresponding Author
B. Mahesh
Department of Chemistry, JSS Academy of Technical Education, Bengaluru, 560 060 Karnataka, India
Correspondence to: B. Mahesh (E-mail: [email protected])Search for more papers by this authorG. S. Nanjundaswamy
Department of Chemistry, JSS Academy of Technical Education, Bengaluru, 560 060 Karnataka, India
Search for more papers by this authorD. Channe Gowda
Department of Studies in Chemistry, Manasagangotri, University of Mysore, Mysuru, 570 006 Karnataka, India
Search for more papers by this authorB. Siddaramaiah
Department of Polymer Science and Technology, Sri Jayachamarajendra College of Engineering, JSS Science & Technology University, Mysuru, 570 006 Karnataka, India
Search for more papers by this authorABSTRACT
The parent repeating sequence of elastin, poly(GVGVP), was synthesized using solution phase method and characterized by 13C- and 1H-NMR spectroscopy. In order to study the polymer–polymer interactions between poly(GVGVP) and hydroxyl propyl methyl cellulose (HPMC), the blends were prepared both in aqueous and solid phase and examined using various analytical techniques. The viscometric measurements have been carried out at 24 °C and the interaction parameters such as α, β, µ, and Δ[η]m revealed the miscible nature of the poly(GVGVP)/HPMC blend systems. In addition, Fourier-transform infrared spectroscopy showed the formation of strong intermolecular hydrogen bond between poly(GVGVP) and HPMC networks. This result was further supported by glass transition temperature (Tg), scanning electron microscopic, and X-ray diffraction studies. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45283.
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REFERENCES
- 1 Floss, D. M.; Schallau, K.; Rose-John, S.; Conrad, U.; Scheller, J. Trends Biotechnol. 2010, 28, 37.
- 2 Kowalczyk, T.; Hnatuszko-Konka, K.; Gerszberg, A.; Kononowicz, A. K. World J. Microbiol. Biotechnol. 2014, 30, 2141.
- 3 Urry, D. W. Angew. Chem. Int. Ed. Engl. 1993, 32, 819.
- 4Van Eldijk, M. B.; McGann, C. L.; Kristi, L.; Kiick, K. L.; van Hest, J. C. Top. Curr. Chem. 2012, 310, 71.
- 5 Lee, J.; Macosko, C. W.; Urry, D. W. Macromolecules 2001, 34, 5968.
- 6 Urry, D. W. J. Phys. Chem. B 1997, 101, 11007.
- 7 Urry, D. W.; Parker, T. M.; Reid, M. C.; Gowda, D. C. J. Bioact. Compat. Polym. 1991, 6, 263.
- 8 Lynne, D.; Hoban, D. V. M.; Marissa Pierce Jerry Quance, D. V. M.; Isaac Hayward, D. V. M.; Adam Mckee, D. V. M.; Channe Gowda, D.; Urry, D. W.; Williams, T. J. Surg. Res. 1994, 56, 179.
- 9 MacPherson, D. T.; Xu, J.; Urry, D. W. Protein Expr. Purif. 1996, 7, 51.
- 10 Lee, J.; Macosko, C. W.; Urry, D. W. Biomacromolecules 2001, 2, 170.
- 11De Silva, D. J.; Olver, J. M. Ophthal. Plast. Reconstr. Surg. 2005, 21, 301.
- 12 Williams, R. O.; Sykora, M. A.; Mahaguna, V. AAPS Pharm. Sci. Technol. 2001, 2, E8.
- 13 Phadtare, D.; Phadtare, G.; Nilesh, B.; Asawat, M. World J. Pharm. Pharm. Sci. 2014, 3, 551.
- 14 Kajal, G.; Chakrabarty, S.; Nanda, A. Der. Pharm. Sin. 2011, 2, 152.
- 15 Sawatari, C.; Kondo, T. Macromolecules 1999, 32, 1949.
- 16 Lio, K.; Minoura, N.; Nagura, M. Polymer 1995, 36, 2579.
- 17 Sionkowska, A. Prog. Polym. Sci. 2011, 36, 1254.
- 18 Dinjaski, N.; Kaplan, D. L. Curr. Opin. Biotechnol. 2016, 39, 1.
- 19 Kondo, T.; Sawatari, C.; Manley, R. S. J.; Derek, G. G. Macromolecules 1994, 27, 210.
- 20 Park, J. S.; Park, J. W.; Ruckenstein, E. Polymer 2001, 42, 4271.
- 21 Nishio, Y.; John Manley, R. S. Macromolecules 1988, 21, 1270.
- 22 Flory, P. J. J. Chem. Phys. 1942, 10, 51.1941, 9, 660–661.
- 23 Huggins, M. L. J. Chem. Phys. 1941, 9, 440.
- 24 Huggins, M. L. J. Am. Chem. Soc. 1942, 64, 2716.
- 25 Khan, Z.; Kaleem Baloch, M. Polym. Bull. 2013, 70, 2015.
- 26 Zhu, G.-Q.; Wang, F.-G.; Gao, Q.-C.; Liu, Y.-Y. Polym. Plast. Technol. Eng. 2012, 51, 966.
- 27 Zhu, G.-Q.; Li, G.-C.; Wang, P. Polym. Plast. Technol. Eng. 2011, 50, 1470.
- 28 Zhu, G.; Wang, F.; Tan, H.; Xu, K.; Liu, Y. Res. Chem. Intermed. 2015, 41, 2285.
- 29 Shiao, W. K.; Chen, C.-J. Macromolecules 2011, 44, 7315.
- 30 Shiao, W. K.; Chen, C.-J. Macromolecules 2012, 45, 2442.
- 31 Lu, Y.-S.; Lin, Y.-C.; Kuo, S.-W. Macromol. 2012, 45, 6547.
- 32 Murata, K.; Kono, H.; Katoh, E.; Kuroki, S.; Ando, I. Polymer 2003, 44, 4021.
- 33 Mahesh, B.; Nanjundaswamy, G. S.; Channe Gowda, D.; Siddaramaiah, J. Appl. Polym. Sci. 2016, 134, DOI: 10.1002/app.44624.
- 34 Baba, A. R.; Gowda, D. C. Lett. Pept. Sci. 2002, 8, 309.
- 35 Mruthyunjaya Swamy, T. M.; Siddaramaiah, J. Macromol. Sci: A Pure Appl. Chem. 2007, 44, 321.
- 36 Chee, K. K. Eur. Polym. Mater. 1990, 26, 423.
- 37 Hong, P.-D.; Hsing-Tsai, H.; Che-Min, C. Polym. Int. 2000, 49, 407.
- 38 Garcia, R.; Melad, O.; Gomez, C. M.; Figueruelo, J. E.; Campos, A. Eur. Polym. J. 1999, 35, 47.
- 39 Mruthyunjaya Swamy, T. M.; Siddaramaiah, J. Appl. Polym. Sci. 2007, 104, 2048.
- 40 Jiang, W. H.; Han, S. J. Eur. Polym. J. 1998, 34, 1579.
- 41 Sun, Z. H.; Wang, W.; Feng, Z. L. Eur. Polym. J. 1992, 28, 1259.
- 42 Schmidt, P.; Dybal, J.; Rodriguez-Cabello, J. C.; Reboto, V. Biomacromolecules 2005, 6, 697.
- 43 Silverstein Robert, M.; Webster Francis, X.; Kiemle David, J. Spectrometric Identification of Organic Compounds, 7th ed.; Wiley: United states of America, 2005.
- 44 Luo, Q.; Chen, Z.; Xuefei, H.; Qiangsong, Z.; Yucheng, Z. Int. J. Biol. Macromol. 2013, 61, 135.
- 45 Shabbir, S.; Zulfiqar, S.; Ishaq, M.; Ilyas Sarwar, M. Colloid Polym. Sci. 2008, 286, 673.
- 46
Rodriguez-Cabello, J. C.;
Alonso, M.;
Diez, M. I.;
Caballero, M. I.;
Herguedas, M. M. Macromol. Chem. Phys. 1999, 200, 1831.
10.1002/(SICI)1521-3935(19990801)200:8<1831::AID-MACP1831>3.0.CO;2-V CAS Web of Science® Google Scholar
- 47 McPhillips, H.; Craig, D. Q.; Royall, P. G.; Hill, V. L. Int. J. Pharm. 1999, 180, 83.
- 48 Fox, T. G.; Flory, P. J. J. Appl. Phys. 1950, 21, 581.
- 49 Wilson Cheung, Y.; Guest Martin, J. J. Polym. Sci. Part B: Polym. Phys. 2000, 38, 2976.
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