Volume 48, Issue 2 pp. 343-354
Article
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pH-sensitivity of hydrogels based on complex forming chitosan: Polyether interpenetrating polymer network

Kang De Yao

Corresponding Author

Kang De Yao

Department of Materials Science and Engineering, Tianjin University (300072), Tianjin, People's Republic of China

Department of Materials Science and Engineering, Tianjin University (300072), Tianjin, People's Republic of China===Search for more papers by this author
Tao Peng

Tao Peng

Department of Materials Science and Engineering, Tianjin University (300072), Tianjin, People's Republic of China

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M. F. A. Goosen

M. F. A. Goosen

Department of Chemical Engineering, Queen's University, Kingston Canada K7L 3N6

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Ji Mei Min

Ji Mei Min

National Laboratory of Natural and Biomimetic Drugs, Beijing Medical University, P. O. Box 216, Beijing (100083), People's Republic of China

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Yu Yin He

Yu Yin He

National Laboratory of Natural and Biomimetic Drugs, Beijing Medical University, P. O. Box 216, Beijing (100083), People's Republic of China

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First published: 10 April 1993
Citations: 116

Abstract

This article deals with a novel, semi-interpenetrating polymer network (semi-IPN), composed of crosslinked chitosan (cr-CS) with glutaraldehyde (GA) and polyether. The pH responsibility of swelling data shows that swelling reaches a maximum at pH = 3.19 and a minimum at pH = 13. The concentration of chitosan acetic acid solution, the amount of crosslinking agent, and polyether, have effects on the swelling behavior of the network. Stimulating-response of the semi-IPN, induced by abrupt changes of pH between 1 and 13, is discussed as well. © 1993 John Wiley & Sons, Inc.

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