Volume 61, Issue 31 e202209207
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Inside Back Cover: A DNA Barcode-Based Aptasensor Enables Rapid Testing of Porcine Epidemic Diarrhea Viruses in Swine Saliva Using Electrochemical Readout (Angew. Chem. Int. Ed. 31/2022)

Amanda Victorious

Amanda Victorious

School of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1 Canada

These authors contributed equally to this work.

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Dr. Zijie Zhang

Dr. Zijie Zhang

Department of Biochemistry and Biomedical Sciences, McMaster University, Canada

These authors contributed equally to this work.

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Dr. Dingran Chang

Dr. Dingran Chang

Department of Biochemistry and Biomedical Sciences, McMaster University, Canada

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Roderick Maclachlan

Roderick Maclachlan

Department of Engineering Physics, McMaster University, Canada

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Dr. Richa Pandey

Dr. Richa Pandey

School of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1 Canada

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Jianrun Xia

Jianrun Xia

Department of Biochemistry and Biomedical Sciences, McMaster University, Canada

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Jimmy Gu

Jimmy Gu

Department of Biochemistry and Biomedical Sciences, McMaster University, Canada

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Prof. Dr. Todd Hoare

Prof. Dr. Todd Hoare

School of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1 Canada

Department of Chemical Engineering, McMaster University, Canada

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Prof. Dr. Leyla Soleymani

Corresponding Author

Prof. Dr. Leyla Soleymani

School of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1 Canada

Department of Engineering Physics, McMaster University, Canada

Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Canada

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Prof. Dr. Yingfu Li

Corresponding Author

Prof. Dr. Yingfu Li

School of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1 Canada

Department of Biochemistry and Biomedical Sciences, McMaster University, Canada

Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Canada

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First published: 07 July 2022

Graphical Abstract

Rapid and reagent-free pathogen tests are urgently needed. In their Research Article (e202204252), Leyla Soleymani, Yingfu Li and co-workers developed a dual-electrode electrochemical chip (DEE-Chip) and a barcode-releasing electroactive aptamer for rapid on-farm detection of porcine epidemic diarrhea viruses (PEDv). In contrast to current biosecurity surveillance with turnaround times of 2–4 days, this technology identifies infection with PEDv in pig saliva in one hour with a diagnostic sensitivity of 100 % and specificity of 83 %.

    The full text of this article hosted at iucr.org is unavailable due to technical difficulties.