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Back Cover: Transition-Metal-Free Hydrogen Autotransfer: Diastereoselective N-Alkylation of Amines with Racemic Alcohols (Angew. Chem. Int. Ed. 31/2019)

Miao Xiao

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

These authors contributed equally to this work.

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Xin Yue,

Xin Yue

State Key Laboratory of Chemical Resource Engineering, Institute of Computational Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing, 100029 China

These authors contributed equally to this work.

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Ruirui Xu,

Ruirui Xu

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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Prof. Dr. Weijun Tang,

Prof. Dr. Weijun Tang

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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Prof. Dr. Dong Xue,

Prof. Dr. Dong Xue

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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Prof. Dr. Chaoqun Li,

Prof. Dr. Chaoqun Li

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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Prof. Dr. Ming Lei,

Corresponding Author

Prof. Dr. Ming Lei

[email protected]

orcid.org/0000-0001-5765-9664

State Key Laboratory of Chemical Resource Engineering, Institute of Computational Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing, 100029 China

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Prof. Dr. Jianliang Xiao,

Corresponding Author

Prof. Dr. Jianliang Xiao

[email protected]

orcid.org/0000-0003-2010-247X

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

Department of Chemistry, University of Liverpool, Liverpool, L69 7ZD UK

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Prof. Dr. Chao Wang,

Corresponding Author

Prof. Dr. Chao Wang

[email protected]

orcid.org/0000-0003-4812-6000

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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Miao Xiao,

Miao Xiao

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

These authors contributed equally to this work.

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Xin Yue,

Xin Yue

State Key Laboratory of Chemical Resource Engineering, Institute of Computational Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing, 100029 China

These authors contributed equally to this work.

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Ruirui Xu,

Ruirui Xu

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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Prof. Dr. Weijun Tang,

Prof. Dr. Weijun Tang

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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Prof. Dr. Dong Xue,

Prof. Dr. Dong Xue

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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Prof. Dr. Chaoqun Li,

Prof. Dr. Chaoqun Li

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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Prof. Dr. Ming Lei,

Corresponding Author

Prof. Dr. Ming Lei

[email protected]

orcid.org/0000-0001-5765-9664

State Key Laboratory of Chemical Resource Engineering, Institute of Computational Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing, 100029 China

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Prof. Dr. Jianliang Xiao,

Corresponding Author

Prof. Dr. Jianliang Xiao

[email protected]

orcid.org/0000-0003-2010-247X

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

Department of Chemistry, University of Liverpool, Liverpool, L69 7ZD UK

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Prof. Dr. Chao Wang,

Corresponding Author

Prof. Dr. Chao Wang

[email protected]

orcid.org/0000-0003-4812-6000

Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062 China

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First published: 10 July 2019

https://doi.org/10.1002/anie.201908296

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Graphical Abstract

A practical method for the synthesis of α-chiral amines that is based on the alkylation of amines with alcohols and does not require any transition-metal catalysts is described by M. Lei, J. L. Xiao, C. Wang, and co-workers in their Research Article on page 10528 ff. With a ketone and NaOH as co-catalysts, racemic alcohols react with Ellman's chiral sulfinamide, affording chiral amines with high diastereoselectivities. This method also provides access to chiral deuterium-labeled amines and drug molecules.

Volume58, Issue31

July 29, 2019

Page 10762

Back Cover: Transition-Metal-Free Hydrogen Autotransfer: Diastereoselective N-Alkylation of Amines with Racemic Alcohols (Angew. Chem. Int. Ed. 31/2019)

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Back Cover: Transition-Metal-Free Hydrogen Autotransfer: Diastereoselective N-Alkylation of Amines with Racemic Alcohols (Angew. Chem. Int. Ed. 31/2019)

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