Volume 57, Issue 23 p. 6708
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Inside Cover: Polyvalent Display of Biomolecules on Live Cells (Angew. Chem. Int. Ed. 23/2018)

Dr. Peng Shi

Dr. Peng Shi

Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802 USA

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Nan Zhao

Nan Zhao

Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802 USA

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Dr. Jinping Lai

Dr. Jinping Lai

Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802 USA

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James Coyne

James Coyne

Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802 USA

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Dr. Erin R. Gaddes

Dr. Erin R. Gaddes

Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802 USA

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Prof. Yong Wang

Corresponding Author

Prof. Yong Wang

Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802 USA

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First published: 14 April 2018

Graphical Abstract

Supramolecular engineering of cell surfaces was explored as a means to display polyvalent biomolecules on live cells using branched DNA polymers. In their Communication on page 6800 ff., Y. Wang et al. show that by using polyvalent surface display of biomolecules, the ability of engineered cells to recognize the microenvironment can be enhanced by at least an order of magnitude.

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