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Back Cover: Biodegradable Inorganic Nanovector: Passive versus Active Tumor Targeting in siRNA Transportation (Angew. Chem. Int. Ed. 14/2016)
Graphical Abstract
Layered double hydroxide nanovectors conjugated with targeting ligands and loaded with therapeutic siRNA are delivered into tumor tissues and cancer cells by exploiting the enhanced permeability and retention effect and ligand-receptor interactions. In their Communication on page 4582 ff. J.-H. Choy et al. report the inhibition of in vivo tumor growth and suppression of specific gene products through the biodegradable inorganic LDHs.
