“My greatest achievement has been the success of my students and postdocs. The most exciting thing about my research is the ability to move to new topics and explore exciting frontiers …︁” This and more about Joseph Wang can be found on page 6304.
Angew. Chem. Int. Ed.2008, 47, 9349–9351. In this paper we demonstrated how the composition of catalytic micromotors can be tailored to impart remarkable power and speed into these tiny machines.
2“Micromachine-Enabled Capture and Isolation of Cancer Cells in Complex Media”: S. Balasubramanian, D. Kagan, C.-M. J. Hu, S. Campuzano, M. J. Lobo-Castañon, N. Lim, D. Y. Kang, M. Zimmerman, L. Zhang, J. Wang, Angew. Chem.2011, 123, 4247–4250;
Angew. Chem. Int. Ed.2011, 50, 4161–4164. This study demonstrates for the first time the ability of man-made micromachines to propel in biological fluids and to isolate circulating tumor cells from complex media.
3“A Self-Powered ‘Sense-Act-Treat’ System that is Based on a Biofuel Cell and Controlled by Boolean Logic”: M. Zhou, N. Zhou, F. Kuralay, J. R. Windmiller, S. Parkhomovsky, G. Valdés-Ramírez, E. Katz, J. Wang, Angew. Chem.2012, 124, 2740–2743;
Angew Chem. Int. Ed.2012, 51, 2686–2689. This article introduces the concept of logic-activated therapeutic intervention, which could serve as the core component of an autonomous medical diagnostic and intelligent drug-delivery system that circumvents the need for external power sources, control electronics, or microelectromechanical actuators.
4“Acoustic Droplet Vaporization and Propulsion of Perfluorocarbon-Loaded Microbullets for Targeted Tissue Penetration and Deformation”: D. Kagan, M. J. Benchimol, J. C. Claussen, E. Chuluun-Erdene, S. Esener, J. Wang, Angew. Chem.2012, 124, 7637–7640;
Angew. Chem. Int. Ed.2012, 51, 7519–7522. This paper introduces a new type of micromachine that owes its amazing power to ultrasound, which explosively vaporizes tiny drops of liquid, accelerating the machines like bullets. These powerful fuel-free microbullets could be used one day to drive drugs deep into diseased tissue or shoot genes into cell nuclei for gene therapy.
5“Epidermal Biofuel Cells: Energy Harvesting from Human Perspiration”: W. Jia, G. Valdés-Ramírez, A. J. Bandodkar, J. R. Windmiller, J. Wang, Angew. Chem.2013, 125, 7374–7377;
Angew Chem. Int. Ed.2013, 52, 7233–7236. This study demonstrates for the first time the ability to harvest bioenergy by using a fuel found on human skin—lactate in sweat.
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