In Situ Generation of Diimide from Hydrazine and Oxygen: Continuous-Flow Transfer Hydrogenation of Olefins†
Bartholomäus Pieber
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.net
Search for more papers by this authorDr. Sabrina Teixeira Martinez
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.net
Search for more papers by this authorDr. David Cantillo
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.net
Search for more papers by this authorCorresponding Author
Prof. C. Oliver Kappe
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.net
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.netSearch for more papers by this authorBartholomäus Pieber
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.net
Search for more papers by this authorDr. Sabrina Teixeira Martinez
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.net
Search for more papers by this authorDr. David Cantillo
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.net
Search for more papers by this authorCorresponding Author
Prof. C. Oliver Kappe
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.net
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, 8010 Graz (Austria) http://www.maos.netSearch for more papers by this authorThis work was supported by a grant from the Christian Doppler Research Society (CDG). We gratefully thank Prof. Walter Goessler for performing ICP-MS measurements. S.T.N. thanks CNPq for a fellowship. D.C. thanks the Research, Technological Innovation, and Supercomputing Center of Extremadura (CénitS) for their support in the use of LUSITANIA computer resources.
Graphical Abstract
No catalyst required! A highly efficient, catalyst-free process to generate diimide in situ from hydrazine monohydrate and molecular oxygen for the selective reduction of alkenes has been developed. The use of a gas–liquid segmented flow system allowed safe operating conditions and dramatically enhanced this atom-economical reaction, resulting in short processing times.
Supporting Information
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References
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