Volume 52, Issue 4 pp. 1156-1160
Communication

Periodic Mesoporous Organosilica-Based Nanocomposite Hydrogels as Three-Dimensional Scaffolds

Dr. Nermin Seda Kehr

Corresponding Author

Dr. Nermin Seda Kehr

Physikalisches Institut and Center for Nanotechnology, Westfälische Wilhelms-Universität Münster, Heisenbergstrasse 11, 48149 Münster (Germany)

Physikalisches Institut and Center for Nanotechnology, Westfälische Wilhelms-Universität Münster, Heisenbergstrasse 11, 48149 Münster (Germany)Search for more papers by this author
Eko Adi Prasetyanto

Eko Adi Prasetyanto

Physikalisches Institut and Center for Nanotechnology, Westfälische Wilhelms-Universität Münster, Heisenbergstrasse 11, 48149 Münster (Germany)

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Kathrin Benson

Kathrin Benson

Institut für Biochemie, Westfälische Wilhelms-Universität Münster, Wilhelm-Klemm-Strasse 2, 48149 Münster (Germany)

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Bahar Ergün

Bahar Ergün

Department of Chemistry, Biochemistry Division, Hacettepe University, 06800 Ankara (Turkey)

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Anzhela Galstyan

Anzhela Galstyan

Physikalisches Institut and Center for Nanotechnology, Westfälische Wilhelms-Universität Münster, Heisenbergstrasse 11, 48149 Münster (Germany)

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Prof. Hans-Joachim Galla

Prof. Hans-Joachim Galla

Institut für Biochemie, Westfälische Wilhelms-Universität Münster, Wilhelm-Klemm-Strasse 2, 48149 Münster (Germany)

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First published: 03 December 2012
Citations: 73

This work has been supported by DFG (SFB 858).

Graphical Abstract

Dye-loaded periodic mesoporous organosilica particles functionalized with bioactive molecules were used for the generation of a nanocomposite alginate hydrogel. The affinity of cells was up to four times higher with the embedded particles than with simple alginate hydrogel, caused by both the nanometer-scale particle itself and its bioactive functionalization.

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