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Arynes in Transition-Metal-Free Multicomponent Coupling Reactions†
†
Generous financial support from CSIR-NCL in the form of a start-up grant for a new faculty is kindly acknowledged. S.S.B. would like to thank CSIR-New Delhi for the award of Junior Research Fellowship. We also thank Anup Bhunia for helpful discussions.
Graphical Abstract
Let's couple together! The multicomponent reactions involving arynes offer direct access to unusual heterocyclic scaffolds and 1,2-disubstituted arenes. This transition-metal-free, one-pot construction of molecular complexity is likely to play a pivotal role in various carbon–carbon and carbon–heteroatom bond-forming reactions.
