Volume 49, Issue 41 pp. 7405-7421
Review

Telomeres and Telomerase: The Means to the End (Nobel Lecture)

Prof. Elizabeth H. Blackburn

Prof. Elizabeth H. Blackburn

Department of Biochemistry and Biophysics, The University of California San Francisco, San Francisco, CA 94158 (USA)

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First published: 06 September 2010
Citations: 188

Copyright© The Nobel Foundation 2009. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.

Graphical Abstract

Secrets revealed: The Nobel Prize for Medicine 2009 was awarded for the solution to one of the greatest mysteries of biology: how are chromosomes copied upon cell division and protected from degradation? The answer can be found at the ends of the chromosomes—the telomeres—and in the enzyme that forms them—telomerase. The laureates describe the events leading to the discovery first-hand.

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