Peptide–Polymer Hybrid Nanotubes†
We thank the following people for their assistance with the analysis of cyclic peptides and polymer hybrid materials: Dr. J. Wörth and C. Warth (ESI MS and LC–MS), Dr. M. Ade (X-ray diffraction), Dr. R. Thomann and A. Neub (TEM), and K. Shroff (automated peptide synthesis). Financial support came from the Deutsche Forschungsgemeinschaft (Emmy Noether Programm), the Landesstiftung Baden-Württemberg (Eliteförderprogramm Nachwuchswissenschaftler), and the Fonds der Chemischen Industrie. J.C. thanks the DAAD for a fellowship with the postgraduate student exchange program. We thank Prof. J. Rühe and Dr. O. Prucker for valuable support and stimulating discussions.
Graphical Abstract
Disguise tactics: Peptide–polymer hybrid nanotubes are constructed in which self-assembled cyclic peptides govern the structure, and a synthetic polymer coating determines the surface chemistry. Formation of the latter is initiated in situ from preorganized peptide building blocks. The picture shows an AFM image of nanotubes on a silicon wafer.
