A Non-Peptidic Ion Channel with K+ Selectivity
Dr. Yasutaka Tanaka
Department of Materials Science, Faculty of Engineering Shizuoka University Hamamatsu, Shizuoka 432 (Japan) Telefax: Int. code + (53)473-4170
Search for more papers by this authorCorresponding Author
Prof. Dr. Yoshiaki Kobuke
Department of Materials Science, Faculty of Engineering Shizuoka University Hamamatsu, Shizuoka 432 (Japan) Telefax: Int. code + (53)473-4170
Department of Materials Science, Faculty of Engineering Shizuoka University Hamamatsu, Shizuoka 432 (Japan) Telefax: Int. code + (53)473-4170Search for more papers by this authorDr. Yasutaka Tanaka
Department of Materials Science, Faculty of Engineering Shizuoka University Hamamatsu, Shizuoka 432 (Japan) Telefax: Int. code + (53)473-4170
Search for more papers by this authorCorresponding Author
Prof. Dr. Yoshiaki Kobuke
Department of Materials Science, Faculty of Engineering Shizuoka University Hamamatsu, Shizuoka 432 (Japan) Telefax: Int. code + (53)473-4170
Department of Materials Science, Faculty of Engineering Shizuoka University Hamamatsu, Shizuoka 432 (Japan) Telefax: Int. code + (53)473-4170Search for more papers by this authorGraphical Abstract
The resorcinol–octadecanal cyclotetramer 1 forms an ion channel in planar lipid bilayers. A stable conductance level is observed with well-defined transitions between open and closed states. The channel discriminates K+ from Na+ ions as well as cations from anions (for example, K+ from Cl−), as indicated by permeability ratios of 3 and 20, respectively. Rb+ ions block the K+ ion current.
References
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