Zuschrift
Rhodium-Catalyzed Asymmetric Synthesis of Spirocarbocycles: Arylboron Reagents as Surrogates of 1,2-Dimetalloarenes†
Ryo Shintani Dr.,
Shingo Isobe,
Momotaro Takeda,
Tamio Hayashi Prof. Dr.,
Ryo Shintani Dr.
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502 (Japan), Fax: (+81) 75-753-3988
Search for more papers by this authorShingo Isobe
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502 (Japan), Fax: (+81) 75-753-3988
Search for more papers by this authorMomotaro Takeda
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502 (Japan), Fax: (+81) 75-753-3988
Search for more papers by this authorTamio Hayashi Prof. Dr.
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502 (Japan), Fax: (+81) 75-753-3988
Search for more papers by this authorRyo Shintani Dr.,
Shingo Isobe,
Momotaro Takeda,
Tamio Hayashi Prof. Dr.,
Ryo Shintani Dr.
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502 (Japan), Fax: (+81) 75-753-3988
Search for more papers by this authorShingo Isobe
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502 (Japan), Fax: (+81) 75-753-3988
Search for more papers by this authorMomotaro Takeda
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502 (Japan), Fax: (+81) 75-753-3988
Search for more papers by this authorTamio Hayashi Prof. Dr.
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502 (Japan), Fax: (+81) 75-753-3988
Search for more papers by this author†
Support has been provided in part by a Grant-in-Aid for Scientific Research (S; 19105002) from the Ministry of Education, Culture, Sports, Science, and Technology (Japan).
Graphical Abstract
Von Eninen zu Spirocyclen: Eine Rhodium-Dien-katalysierte Addition von Natriumtetraarylboraten an 2-Cycloalken-1-one mit einer anhängenden Alkineinheit führt zu Spirocarbocyclen. Dabei werden zwei neue C-C-Bindungen durch das Tetraarylborat gebildet, und der chirale Dienligand sorgt für den hoch enantioselektiven Aufbau quartärer Kohlenstoffspirozentren.
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