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Promace day 1/MOPP day 8 chemotherapy for prolymphocytic leukemia: A case report of prolonged survival
Dr. Benjamin H. Yuen,
John E. Godwin,
Corresponding Author
Dr. Benjamin H. Yuen
Department of Medicine, Division of Hematology/Oncology, Loyola University Medical Center, Maywood, Illinois
Division of Hematology/Oncology, Department of Medicine, Loyola University Stritch School of Medicine, Building 54,2160 S. First Avenue, Maywood, IL 60153Search for more papers by this authorJohn E. Godwin
Department of Medicine, Division of Hematology/Oncology, Loyola University Medical Center, Maywood, Illinois
Search for more papers by this authorDr. Benjamin H. Yuen,
John E. Godwin,
Corresponding Author
Dr. Benjamin H. Yuen
Department of Medicine, Division of Hematology/Oncology, Loyola University Medical Center, Maywood, Illinois
Division of Hematology/Oncology, Department of Medicine, Loyola University Stritch School of Medicine, Building 54,2160 S. First Avenue, Maywood, IL 60153Search for more papers by this authorJohn E. Godwin
Department of Medicine, Division of Hematology/Oncology, Loyola University Medical Center, Maywood, Illinois
Search for more papers by this authorAbstract
The treatment result of a case of de novo B-cell prolymphocytic leukemia (B-PLL) is described. The diagnosis was established with histologic, ultrastructural and immunologic studies. The patient was treated with chemotherapy using a total of seven cycles of ProMACE Day 1/MOPP Day 8 lymphoma regimen. Complete remission was achieved after 5 cycles of chemotherapy. The patient remains disease free after a 7-year follow up. This is the first case of PLL being treated with such a regimen and the only case reported achieved such prolonged survival. Results of other treatment modalities are reviewed. © 1994 Wiley-Liss, Inc.
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