Chapter 4

Manufacturing of Biomaterials via a 3D Printing Platform

Patrick Thayer

Patrick Thayer

CELLINK LLC, Cambridge, MA, USA

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Hector Martinez

Hector Martinez

CELLINK LLC, Blacksburg, VA, USA

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Erik Gatenholm

Erik Gatenholm

CELLINK LLC, Cambridge, MA, USA

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First published: 14 December 2018
Citations: 1

Summary

In recent years, advances in additive manufacturing, also known as three-dimensional (3D) printing, have attracted great attention as a “new industrial revolution”. The printable biomaterials can be considered a specialized subclass known as bioinks. A biomaterial that possesses shear-thinning properties is a strong indicator that the material can be utilized as a bioink. This chapter discusses bioinks and their unique characteristics that necessitate environmental controls that are integrated into bioprinter systems to facilitate and modulate printability. It focuses on what an advanced bioprinting system such as the BIO X can achieve with all the controls and features necessitated by the materials. Bioprinting can permit precise control over the overall structure of a construct and its microarchitecture within those determined by infill patterns. Bioprinting will play a critical role in the advancement of personalized medicine by enabling the fabrication of patterned and organized constructs and prostheses.

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