Chapter 1

Normal and Abnormal Cardiac Development

Adriana C. Gittenberger-De Groot PhD

Adriana C. Gittenberger-De Groot PhD

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands

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Monique R. M. Jongbloed MD, PhD

Monique R. M. Jongbloed MD, PhD

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands

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Robert E. Poelmann PhD

Robert E. Poelmann PhD

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands

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First published: 13 January 2012
Citations: 2

Summary

In this chapter the main events of cardiac morphogenesis are discussed. Attention is focused on morphologic descriptions and insights based on the molecular biologic approaches in animal models that have enhanced and modified our understanding of normal and abnormal cardiac development, including relevance for adult disease with a developmental background.

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