This chapter contains sections titled:

• Introduction

• Dendritic cell terminology and heterogeneity

• Antigen uptake

• Antigen presentation

• Integrated function of dendritic cells in the immune response

• Role for dendritic cells in allergic sensitization in humans

• Dendritic cells in allergic asthma

• Dendritic cells in atopic dermatitis

• Role of dendritic cells in allergic rhinitis

• Dendritic cells as drug targets in allergic diseases

• Origin and function of macrophages

• Homeostasis in the alveolar compartment is maintained by alveolar macrophages

• Function of alveolar macrophages in inflammatory conditions and asthma

• Conclusion

• References