Chapter 12

Eosinophils: Biological Properties and Role in Health and Disease

Simon P. Hogan

Simon P. Hogan

Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

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Helene F. Rosenberg

Helene F. Rosenberg

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

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Redwan Moqbel

Redwan Moqbel

Division of Pulmonary Medicine, Departments of Medicine, University of Alberta, Edmonton, Alberta, Canada

Medical, Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada

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Simon Phipps

Simon Phipps

Centre for Asthma and Respiratory Diseases, School of Biomedical Sciences, University of Newcastle, Newcastle, New South Wales, Australia

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Paul S. Foster

Paul S. Foster

Centre for Asthma and Respiratory Diseases, School of Biomedical Sciences, University of Newcastle, Newcastle, New South Wales, Australia

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Paige Lacy

Paige Lacy

Division of Pulmonary Medicine, Departments of Medicine, University of Alberta, Edmonton, Alberta, Canada

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A. Barry Kay MD, PhD, FRCP, DSc, FRSE, FMedSci

A. Barry Kay MD, PhD, FRCP, DSc, FRSE, FMedSci

Emeritus Professor of Allergy and Clinical Immunology

National Heart and Lung Institute, Imperial College London, London, UK

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Marc E. Rothenberg

Marc E. Rothenberg

Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

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First published: 25 July 2008
Citations: 2

Summary

This chapter contains sections titled:

  • Introduction

  • Eosinophil granule proteins

  • Eosinophil surface markers

  • Eosinophils and immune regulation

  • Eosinophil development

  • Eosinophil trafficking

  • Role of eosinophils in disease

  • Anti-eosinophil therapeutics

  • Conclusions

  • References

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