More and more hospitals, clinics, and other medical institutions are seriously considering adopting or expanding their 3D-printing capabilities as the technology continues to find more and more uses in the medical field. Recent developments in 3D-printing technology have been welcomed by medical professionals as a strong instrument to aid in the delivery of high-quality patient care with an eye toward sustainability. There is great promise for the use of 3D printing at the point of care (POC) in a hospital or clinic, but its widespread implementation will require careful thought and planning. The authors lay out the foundational ideas and factors to consider while establishing the infrastructure to support 3D printing in a healthcare setting. Creating a digital workflow and contemplating the potential future use of electronic health records are all part of the process. So, too, is developing a business case for doing so. The authors elaborate on the quality and regulatory concerns of medical 3D printing and emphasize the supported applications and benefits of the technology. The supplied data is aimed to serve as a guide for radiology departments interested in learning more about POC 3D printing and perhaps incorporating it into routine clinical practice.