Ultrafast (UF) NMR is capable of delivering a multi-dimensional spectrum in a single scan, i.e., in a few hundreds of milliseconds. This method relies on the spatial encoding of NMR interactions, which enables a parallel acquisition of experiments with various evolution periods in a single step. This approach is much faster than the conventional scheme, in which time incremented experiments are collected consecutively. This versatile concept has been firstly exploited to accelerate classical 2D spectroscopic experiments (COSY, TOCSY, HSQC, HMBC, etc..), but also to spatially encode dynamic parameters (diffusion, relaxation, and exchange). By delivering 2D spectra in a single or a few scans, UF 2D NMR has been applied in many situations where time constraints make 2D conventional methods inaccessible. In this chapter, the principle and the key features of the ultrafast NMR concept are described along with examples of UF 2D experiments. The specificities of this method in terms of sensitivity, resolution and spectral width are discussed with respect to conventional 2D NMR. Finally, a tour of UF 2D NMR applications is presented through some representative examples drawn from the literature.