Chapter 33
New Technologies for Insulin Administration
Book Editor(s):Richard I.G. Holt MA, MB BChir, PhD, FRCP, FHEA,
Allan Flyvbjerg MD, DMSc,
Richard I.G. Holt MA, MB BChir, PhD, FRCP, FHEA
Professor in Diabetes & Endocrinology Faculty of Medicine Honorary Consultant Physician
Human Development and Health
University of Southampton, Southampton, UK
Southampton National Institute for Health Research Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK
Search for more papers by this authorAllan Flyvbjerg MD, DMSc
Former CEO at Steno Diabetes Center Copenhagen (SDCC) Professor of Clinical Endocrinology
The Capital Region of Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Search for more papers by this authorFirst published: 12 January 2024
Summary
Insulin pen technology has significantly advanced since the first pen was launched by Novo Nordisk in 1985 and now ‘smart’ connected pens are available, which can record the timing and dose of insulin administration and communicate with blood glucose monitoring and continuous glucose monitoring systems. In this chapter, the authors discuss a range of new technologies for insulin delivery and review the available evidence investigating their use in clinical practice. Injection ports are a viable alternative to subcutaneous insulin injections. The main advantages of continuous subcutaneous insulin infusion are the ability to vary basal rates and the ease of delivery of multiple and more frequent boluses. The evidence base for pumps is derived from both randomized controlled trials and rea-world evidence. The greatest risk of intensive insulin treatment is hypoglycaemia. Insulin pumps are manufactured with either steel or Teflon cannulas.
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