Chapter 21

In-Stent Restenosis in the New Generation DES Era

First published: 06 May 2022
Citations: 1

Summary

In-stent restenosis has been common after bare metal stent implantation and its classification is prognostically important. Drug eluting stents restenose less often; imaging can clarify the different mechanism operational in a particular case and allow development of a rational treatment plan. Neoatherosclerosis is a new mechanism for very late occurring stent restenosis. A new drug eluting stent is used in restenosis extending outside stent edges and after a partially successful results of other devices in different types of cases. Adding multiple layers of stents is generally undesirable; drug eluting balloons may offer a useful alternative. Atherectomy may be used to debulk extensive neointimal hyperplasia. Coronary bypass surgery is useful in recurrent restenosis and multivessel disease with good distal targets. Brachytherapy remains a palliative option.

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