Chapter 3

Carbon Nanomaterials for Optical Bioimaging and Phototherapy

Haifeng Dong

Haifeng Dong

Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology, Beijing, PR China

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Yu Cao

Yu Cao

Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology, Beijing, PR China

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First published: 26 November 2018
Citations: 5

Summary

This chapter covers the recent progress in optical biological imaging analysis and phototherapies using carbon nanomaterials. Different carbon nanomaterials require different strategies of surface functionalization to make them soluble in aqueous environment and compatible with cells and tissues. Several spectroscopic techniques can be utilized for biological in vitro and in vivo imaging. One of the most common techniques is fluorescence imaging. Carbon nanomaterials can be used for their intrinsic fluorescence properties or can be tagged with fluorescent molecules. Phototherapies, mainly including photothermal therapy (PTT) and photodynamic therapy (PDT), are able to destruct cancer cells upon specific light irradiation. With the help of nanotechnology, phototherapeutic nanoagents could specifically target cancer via either passive or active tumor targeting. In the past few years, phototherapies based on the unique optical and chemical properties of carbon nanomaterials have aroused increasing interest.

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